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Method for preparing phthisic adjuvant with extractum of Periplaneta americana

A technology of Periplaneta americana and tuberculosis, which is applied in the field of medicine, can solve the problems of different and immature, and achieve the effects of preventing spoilage, preventing hydrolysis of active substances, and reducing production costs

Inactive Publication Date: 2013-03-20
KUNMING SINOWAY NATURAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Although there are some disclosures about the extraction method of the American cockroach extract, the American cockroach contains many ingredients, and the ingredients obtained by different extraction methods are also different, and the obtained extracts also have different effects on different diseases.
However, the currently disclosed technology is still immature for the extraction of specific active ingredients of Periplaneta americana for the treatment of certain diseases, and the deep processing and deep extraction for the treatment of specific diseases will become a new development trend

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The method for preparing tuberculosis adjuvant medicine by extracting extract from Periplaneta americana comprises the following steps:

[0027] A, pulverizing: the dry Periplaneta americana body of 200Kg is pulverized, crosses 24 mesh sieves, makes Periplaneta americana meal;

[0028] B, soak: step A gained Periplaneta americana coarse powder is soaked with the ethanol of concentration 95%, makes ethanol liquid level higher than coarse powder liquid level 5cm airtight preservation, makes coarse powder mixed liquor;

[0029] C. Extraction: Put the coarse powder mixture obtained in step B into the extraction tank, and carry out reflux extraction for 3 times at a temperature of 70-85°C. When extracting the coarse powder mixture for the first time, add 1000Kg of ethanol with a concentration of 95% , the extraction time was 4 hours; after the second time, each extraction added 600Kg concentration of 95% ethanol, and the extraction time was 3 hours; the combined extracts wer...

Embodiment 2

[0035] The method for preparing tuberculosis adjuvant medicine by extracting extract from Periplaneta americana comprises the following steps:

[0036] A, pulverizing: the dry Periplaneta americana body of 200Kg is pulverized, crosses 24 mesh sieves, makes Periplaneta americana meal;

[0037] B, soak: step A gained Periplaneta americana coarse powder is soaked with the ethanol of concentration 92%, makes ethanol liquid level higher than coarse powder liquid level 8cm airtight preservation, makes coarse powder mixed solution;

[0038] C. Extraction: Put the coarse powder mixture obtained in step B into the extraction tank, and carry out 4 times of reflux extraction at a temperature of 70 to 85°C. When the coarse powder mixture is extracted for the first time, 1000Kg of ethanol with a concentration of 92%, The extraction time is 5 hours; after the second time, 800Kg of ethanol with a concentration of 92% is added for each extraction, and the extraction time is 4 hours; the extra...

Embodiment 3

[0044] The method for preparing tuberculosis adjuvant medicine by extracting extract from Periplaneta americana comprises the following steps:

[0045] A, pulverizing: the dry Periplaneta americana body of 200Kg is pulverized, crosses 24 mesh sieves, makes Periplaneta americana meal;

[0046] B, soak: step A gained Periplaneta americana coarse powder is soaked with the ethanol of concentration 90%, makes ethanol liquid level higher than coarse powder liquid level 10cm airtight preservation, makes coarse powder mixed solution;

[0047] C. Extraction: Put the coarse powder mixture obtained in step B into the extraction tank, and carry out reflux extraction for 5 times at a temperature of 70 to 85°C. When the coarse powder mixture is extracted for the first time, 1600Kg of ethanol with a concentration of 90%, The extraction time is 6 hours; after the second time, 1200Kg of 90% ethanol is added for each extraction, and the extraction time is 5 hours; the extracts are combined and ...

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PUM

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Abstract

The invention relates to the field of medical technology, and especially relates to a method for preparing a phthisic adjuvant with extractum of Periplaneta Americana. The invention provides the method for preparing a phthisic adjuvant with extractum of Periplaneta Americana, wherein the method comprises the following steps of: A, smashing; B, soaking; C, extracting; D, first concentration; E, degreasing; and F, second concentration. With the method, a lot of proteins in the Periplaneta americana can be removed effectively, the grease removal rate is high, and the oil content of the obtained extract is only 0.30 counted by A(absorbance) / W(Weight). By the alcohol with concentration of 90%-95%, the adjuvant can be prevented from spoilage, the preservation time is prolonged, and the yield of active ingredients is improved. The content of the active ingredients is up to 13%-22%, the cure rate of the prepared medicine to the phthisis is up to 45%, and the total effective rate can be 85%. Hydrolysis of active substances (in the extract) for adjunctive treatment to the phthisis is prevented, and the therapeutic effect of the adjuvant is improved. The production cost is lowered, and the production efficiency is improved.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a method for preparing tuberculosis adjuvant medicine by extracting extract from Periplaneta americana. Background technique [0002] The American cockroach (Periplaneta americana) is the largest insect in the cockroach family. The adult body is 29-35 mm long, reddish brown, and the wings are longer than the end of the abdomen. The tentacles are very long, and there are large butterfly-shaped brown spots in the middle of the pronotum, and the trailing edge of the spots has a complete yellow band. It is native to South America and has a wide range of eating habits. It likes sugar and starch, and pollutes food. [0003] Periplaneta americana is a traditional Chinese medicinal material, and adults are used as medicine. It is cold in nature, salty in taste, poisonous, pungent, and has the functions of dispelling blood stasis, eliminating stagnation, detoxifying, diuresis, and reduc...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61P31/06
Inventor 何道峰郝振平
Owner KUNMING SINOWAY NATURAL PHARMA
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