Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Super resolution optofluidic microscopes for 2D and 3D imaging

一种超分辨率、光流体的技术，应用在用于2D和3D成像的超分辨率光流体显微镜领域，能够解决图像分辨率限制等问题

Active Publication Date: 2012-11-21
CALIFORNIA INST OF TECH
View PDF7 Cites 25 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Also, in many conventional OFMs, the image resolution is limited

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Super resolution optofluidic microscopes for 2D and 3D imaging
  • Super resolution optofluidic microscopes for 2D and 3D imaging
  • Super resolution optofluidic microscopes for 2D and 3D imaging

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0035] Embodiments of the present invention will be described below with reference to the drawings. Some embodiments include a SROFM having a body (eg, a microfluidic chip) that defines a fluidic channel and a photodetector with a two-dimensional array of photodetection elements (eg, a CMOS sensor array). A photodetector samples light data at a subpixel sampling rate, capturing a sequence of subpixel-shifted snapshot projections (frames) as the imaged subject moves through the fluid channel. A processor determines a motion vector of the object. Subsequently, the processor reconstructs a super-resolution (SR) 2D image of the object from the sub-pixel shifted frame sequence and motion vectors using a super-resolution algorithm (SR algorithm). The processor may also determine an SR three-dimensional image of the subject by combining multiple reconstructed HR images (viewpoints) from different angles of incidence using computed tomography.

[0036] Sub-pixel shifting of objects ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
full width at half maximumaaaaaaaaaa
Login to View More

Abstract

A super resolution optofluidic microscope device comprises a body defining a fluid channel having a longitudinal axis and includes a surface layer proximal the fluid channel. The surface layer has a two-dimensional light detector array configured to receive light passing through the fluid channel and sample a sequence of subpixel shifted projection frames as an object moves through the fluid channel. The super resolution optofluidic microscope device further comprises a processor in electronic communication with the two-dimensional light detector array. The processor is configured to generate a high resolution image of the object using a super resolution algorithm, and based on the sequence of subpixel shifted projection frames and a motion vector of the object.

Description

[0001] Cross References to Related Applications [0002] This paper is a non-provisional application of, and claims priority to, US Provisional Patent Application Serial No. 61 / 316,762, entitled "Super-Resolution Optofluidic Microscopy for 2D and 3D Imaging," filed March 23, 2010. The entire content of this provisional application is hereby incorporated by reference for all purposes. [0003] This nonprovisional application is related to the following co-pending and generally assigned patent application, the entire contents of which are hereby incorporated by reference for all purposes: [0004] US Patent Application Serial No. 12 / 398,050, filed March 4, 2009, and entitled "Optofluidic Microscopy Apparatus Using an Array of Photosensors." Background of the invention [0005] Embodiments of the present invention generally relate to optofluidic microscopes (OFMs) and OFM systems. More specifically, certain embodiments relate to super-resolution optofluidic microscopy (SROFM) f...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/49G01N35/00G02B21/32
CPCG02B21/36H04N5/349G06T3/4053G02B21/0008H04N25/48G01N15/1484G01N15/147
Inventor 郑国安杨昌辉塞缪尔·杨李承亚
Owner CALIFORNIA INST OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com