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Pharmaceutical composition for promoting nerve damage restoration and application thereof

A technology of nerve repair and composition, applied in the direction of drug combination, application, drug delivery, etc.

Active Publication Date: 2012-11-14
JIANGSU TONGKAI ZHAOFENG BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Vitamin B 12 Stored in the liver, but easily excreted through urine

Method used

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  • Pharmaceutical composition for promoting nerve damage restoration and application thereof
  • Pharmaceutical composition for promoting nerve damage restoration and application thereof
  • Pharmaceutical composition for promoting nerve damage restoration and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] Embodiment 1: Preparation example of pharmaceutical composition

[0085] A pharmaceutical composition, its component is the compound amino acid injection 500mL that contains 5 kinds of amino acids (wherein L-ornithine is 1.5g, L-aspartic acid is 2.5g, L-arginine is 8.5g, L-glycine is 3.8g, L-threonine is 4.6g), Vit B6 8g is added to 0.9% sodium chloride injection 250mL.

Embodiment 2

[0086] Embodiment 2: Preparation example of pharmaceutical composition

[0087] A pharmaceutical composition, its component is compound amino acid injection 500mL containing: L-ornithine 3.5g, aspartic acid 2.50g, arginine 8.80g, isoleucine 8.80g, leucine 13.60g , lysine 7.51g, methionine 1.20g, phenylalanine 1.60g, threonine 4.60g, tryptophan 1.50g, valine 10.60g, histidine 4.70g, glycine 6.30g, alanine 8.30 g, proline 7.10g, asparagine 0.48g, cysteine ​​0.59g, glutamic acid 5.70g, serine 3.70g, tyrosine 0.67g, Vit B6 5g, Vit C3g, vitamins added to 0.9% Sodium chloride injection 250mL.

Embodiment 3

[0088] Embodiment 3: Preparation example of pharmaceutical composition

[0089] A pharmaceutical composition, its component is compound amino acid injection 500mL containing: L-ornithine 4.5g, aspartic acid 2.80g, arginine 8.30g, isoleucine 6.50g, leucine 12.00g , lysine 7.50g, methionine 1.60g, phenylalanine 1.40g, tryptophan 1.80g, valine 10.60g, histidine 4.80g, glycine 6.20g, alanine 8.50g, proline 7 .l0g, asparagine 0.48g, glutamic acid 5.70g, serine 3.70g, tyrosine 0.67g, Vit B 6 8g, VitB 1 2mg, VitB 2 1mg, pantothenic acid 4mg, biotin 0.2mg, folic acid 0.3mg, VitB l2 6μg, Vit C2g, and vitamins were added to 250mL of 5% glucose sodium chloride injection.

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PUM

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Abstract

The invention belongs to the field of medical health products, and in particular relates to a pharmaceutical composition for promoting nerve injury restoration and an application thereof. The pharmaceutical composition in each unit contains 0.5-8g of L-ornithine, 1-5g of aspartic acid, 3-10g of arginine, 3-10g of vitamin B6, and the balance of accessories and / or other components. The pharmaceutical composition disclosed by the invention can obviously promote the restoration of spinal nerve function, and can be used for preparing medicines of nerve injury restoration; and the pharmaceutical composition has very good curative effect on avute myelitis.

Description

technical field [0001] The invention belongs to the field of medicine and health products, and relates to a pharmaceutical composition for promoting nerve damage repair and application thereof. Background technique [0002] In the 1960s, scientists first confirmed that the central nervous system of mammals has certain endogenous repair properties. The axons and main branches of neurons in the adult brain and spinal cord can be repaired after a certain degree of damage. In adult birds The birth of new neurons in the brains of humans, non-primates, and humans is called neurorepair. Nerve restorative drugs refer to those drugs that promote neuron repair by directly acting on neural stem cells in the human or animal brain, and have the effect of increasing neurons in the brain. The use of medicines for the treatment of diseases. [0003] So far, there are many drugs for the treatment of spinal cord injury, but only methylprednisolone has been affirmed to treat spinal cord inju...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4415A61K31/198A61K31/714A61P25/00A23L1/305A23L1/302A23L1/30A23L33/15
CPCA61K9/0019A61K47/02A61K31/198A61K31/4415A61K47/26A61P25/00A61K2300/00
Inventor 岳茂兴万红贵黄彤舸
Owner JIANGSU TONGKAI ZHAOFENG BIOTECHNOLOGY CO LTD
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