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Preparation method of Bifidobacterium microcapsules

A technology of bifidobacteria and composite microcapsules, which is applied in the field of preparation of bifidobacteria microcapsules, can solve the problems of high production cost and poor operability, and achieve reduced production costs, high survival rate, and improved bioavailability Effect

Inactive Publication Date: 2012-10-31
赵振华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The above two patents have the defects of poor operability and high production cost

Method used

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  • Preparation method of Bifidobacterium microcapsules
  • Preparation method of Bifidobacterium microcapsules

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Experimental program
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Embodiment 1

[0030] A preparation method of bifidobacterium composite microcapsules, the steps are as follows:

[0031] Step 1: Preparation of composite bacterial suspension

[0032] At 30°C, in 100ml of distilled water, add 3g of bifidobacterium strains, 1g of Chinese yam powder that has completely passed through a 100-mesh nylon sieve, and 1g of stachyose that has completely passed through a 100-mesh nylon sieve, stir well, and use a 24-mesh Synthetic fiber sieve filter, the filtrate is the bacterial suspension, ready for use;

[0033] Step 2: Dissolution of wall material

[0034] Add 5g pectin, 1g bitter almond extract, and 1g amomum extract to 100ml distilled water, swell with distilled water at 30°C for 1.5 hours, stir to dissolve, place at 30°C for 6 hours, and ultrasonically remove bubbles, spare;

[0035] Step 3: Add 3g of sodium alginate, 1g of orange peel extract, and 1g of gardenia extract to 100ml of distilled water, swell with distilled water at 30°C for 1.5 hours, ...

Embodiment 2

[0040] Embodiment 2: same as embodiment 1 process, different parts are as follows:

[0041] Step 1: Preparation of composite bacterial suspension

[0042] At 20°C, in 100ml of distilled water, add 5g of bifidobacterium strains, 0.5g of Chinese yam powder that has completely passed through a 100-mesh nylon sieve, and 0.5g of stachyose that has completely passed through a 100-mesh nylon sieve, stir well, and use Filter through a 24-mesh synthetic fiber screen, and the filtrate is the bacterial suspension, which is ready for use;

[0043] Step 2: Dissolution of wall material

[0044] Add 12g of pectin, 0.5g of bitter almond extract, and 0.5g of amomum extract per 100ml of distilled water, swell with distilled water at 20°C for 1 hour, stir to dissolve, and place at 30°C for 5 hours , ultrasonically remove air bubbles, set aside;

[0045] Step 3: Add 5g of sodium alginate, 0.5g of orange peel extract, and 0.5g of gardenia extract per 100ml of distilled water, swell with dis...

Embodiment 3

[0046] Embodiment 3: identical with the technological process of embodiment 1, difference is as follows:

[0047] Step 1: Preparation of composite bacterial suspension

[0048] At 30°C, add 4g of bifidobacterium strains, 0.7g of Chinese yam powder that has completely passed through a 100-mesh nylon sieve, and 0.7g of stachyose that has completely passed through a 100-mesh nylon sieve into 100ml of distilled water, stir well, and use Filter through a 24-mesh synthetic fiber screen, and the filtrate is the bacterial suspension, which is ready for use;

[0049] Step 2: Dissolution of wall material

[0050] According to the ratio of adding 8g pectin, 0.7g bitter almond extract, and 0.7g amomum extract per 100ml of distilled water, add the above three kinds into distilled water, swell with distilled water at 30°C for 1.5 hours, stir to dissolve, Place at 30°C for 6 hours, ultrasonically remove air bubbles, and set aside;

[0051] Step 3: According to the ratio of adding 4g s...

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Abstract

The invention belongs to the technical field of preparation of probiotic products, and particularly relates to a preparation method of Bifidobacterium microcapsules, which comprises the following steps: 1. preparing a composite bacterial suspension; 2. dissolving a wall material; and 3. preparing the composite microcapsules. The invention provides a novel method for preparing Bifidobacterium powder microcapsules, removes the film-forming reaction of chitosan, and lowers the production cost. According to the invention, the Bifidobacterium is embedded into an enteric material isolate the outside air, so that the Bifidobacterium microcapsules are hardly dissolved in gastric acid and slowly release in the intestinal tract; and after the Bifidobacterium microcapsules are digested by the intestinal tract, the bioavailability is enhanced, and the survival rate is higher than the document report.

Description

technical field [0001] The invention belongs to the technical field of preparation of probiotic products, and in particular relates to a preparation method of bifidobacterium microcapsules. Background technique [0002] There are a large number of microorganisms in the normal human intestinal tract, and the balance of these flora plays an important role in human health. The normal flora in the intestinal tract exists as a whole, interdependent and restricting each other, and a series of physiological dysfunction occurs when the intestinal flora is imbalanced, and the clinical manifestations are diarrhea and infection. In recent years, probiotics (agent) (probiotics), as a general term for a class of bacteria that are beneficial to the human body, have special effects on the treatment and prevention of diseases such as diarrhea and infection, and have become a research hotspot in microbiology. Widely used in industry. Bifidobacterium is one of the most popular probiotic...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61K9/50A61P1/10A61K31/702A61K35/74A61K35/745
Inventor 赵振华
Owner 赵振华
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