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Chinese medicinal composition for treating carbonylation metal poisoning and preparation method thereof

A technology of traditional Chinese medicine and medicine, applied in the field of Chinese medicine extract composition, can solve the problems that the effect needs to be evaluated and affect the clinical treatment of acute nickel carbonyl poisoning, and achieve the effects of reducing the degree of fracture, good anti-oxidative damage, and reducing the ability of genetic damage

Inactive Publication Date: 2012-10-31
程宁 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, hormones, nickel drive and symptomatic treatment are mainly used for acute poisoning of metal carbonyl-nickel carbonyl at home and abroad, but the effect of related therapeutic drugs needs to be evaluated, which seriously affects the clinical treatment of acute nickel carbonyl poisoning

Method used

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  • Chinese medicinal composition for treating carbonylation metal poisoning and preparation method thereof
  • Chinese medicinal composition for treating carbonylation metal poisoning and preparation method thereof
  • Chinese medicinal composition for treating carbonylation metal poisoning and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A traditional Chinese medicine compound preparation, which is prepared by extracts of four kinds of Chinese herbal medicines into an injection. The weight ratio of the extracts in the specific formula is: 33% ginsenoside, 33% aconite alkaloid, 17% total tanshinone, and 17% glycyrrhizic acid .

[0026] The preparation of the Chinese medicine compound injection is carried out successively according to the following steps:

[0027] (1) Ginsenosides were extracted by ultrasonic water extraction.

[0028] (2) Aconitum alkaloids were extracted by water extraction and ethanol precipitation method.

[0029] (3) Total tanshinone was extracted by ethanol method.

[0030] (4) Glycyrrhizic acid was extracted by water-soluble method.

[0031] (5) Prepare the above four extracts in a certain proportion, add water for injection to fully dissolve, adjust the concentration of each traditional Chinese medicine to 0.2mg / ml, adjust the pH value to 4-6, refrigerate for 48 hours, filter, ...

Embodiment 2

[0033] A compound traditional Chinese medicine preparation, which is prepared by extracting four kinds of Chinese herbal medicines into an injection, specifically: 30% ginsenoside; 36% aconite alkaloid; 14% total tanshinone; 20% glycyrrhizic acid.

[0034] Its extraction and preparation methods are the same as the examples.

Embodiment 3

[0036] A compound traditional Chinese medicine preparation, which is prepared by extracting four kinds of Chinese herbal medicines into an injection, specifically: ginsenoside accounts for 28%, aconite alkaloid accounts for 38%, total tanshinone accounts for 12% and glycyrrhizic acid accounts for 22%.

[0037] Its extraction and preparation methods are the same as the examples.

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Abstract

The invention relates to a Chinese medicinal composition injection for treating chemical injuries caused by carbonylation metal poisoning, in particular to a compound injection prepared by extracting active ingredients from ginsenoside, prepared common monkshood daughter root alkaloid, tanshinone and glycyrrhizic acid, and extraction and preparation methods of a Chinese medicinal composition. The injection is easy to prepare, is low in price, has good treatment and restoration effects on injuries of target organs (lung, liver, kidney, spleen and lymphocytes) after nickel carbonyl acute poisoning, and plays positive roles in maintaining the health of nickel contract employees in industrial production and guaranteeing rapid development of enterprises; and an effective preparation is provided for clinical treatment of carbonylation metal poisoning.

Description

Technical field [0001] The patent of the present invention relates to a traditional Chinese medicine extract composition for treating chemical damage caused by metal carbonylate poisoning. Specifically, the compound injection prepared from ginsenoside, aconite alkaloid, tanshinone and glycyrrhizic acid, and the extraction and preparation method of the traditional Chinese medicine composition. Background technique [0002] Acute poisoning of carbonyls is often encountered in carbonylation metallurgical industrial production. Acute inhalation of carbonyl compounds by humans or animals can cause lung, liver, kidney, brain and other multi-organ damage. In recent years, hormones, nickel repellent and symptomatic treatment have been mainly used for acute poisoning of metal carbonyl-nickel carbonyl at home and abroad, but the effect of related therapeutic drugs has yet to be evaluated, which has seriously affected the clinical treatment of acute nickel carbonyl poisoning. Therefo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/714A61P39/02A61K31/58A61K31/704
Inventor 程宁王秋英
Owner 程宁
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