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Ultrafine traditional Chinese medicinal granule piece and preparation process thereof

A technology of ultra-fine particles and traditional Chinese medicine, which is applied in pharmaceutical formulations, devices for making medicines into special physical or taking forms, and medical preparations containing active ingredients. rules and other issues to ensure safety, rapid absorption, and good curative effect.

Active Publication Date: 2012-10-17
SICHUAN JINSUIFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In view of the existing granulation process and equipment for Chinese herbal medicines with low viscosity, the prepared granules have the defects of irregular shape, easy moisture absorption and poor fluidity, and provided a new production process for preparing Chinese medicine ultrafine particle decoction pieces

Method used

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  • Ultrafine traditional Chinese medicinal granule piece and preparation process thereof
  • Ultrafine traditional Chinese medicinal granule piece and preparation process thereof
  • Ultrafine traditional Chinese medicinal granule piece and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment 1 hippocampus

[0048] 1. Existing methods:

[0049] 1. Wine making (1): Brush off the dust, put it in a wire sieve, and crisp it with a slow fire. After roasting, spray an appropriate amount of white wine from the fire, and then crisp it. Repeat several times until it is deep yellow and let it cool. Get it immediately (or grind it into powder); for every 10kg of hippocampus, use 2kg of white wine. or

[0050] 2. Wine making (2): Take the hippocampus and soak it with wine, and put it next to the stove to dry or sun-dry.

[0051] 2. Method 1:

[0052] 1. Wine making (1):

[0053] A, take hippocampus, pulverize to pass 80-100 mesh sieve;

[0054] B. Put it on an iron plate and crisp it with a slow fire. After roasting, spray an appropriate amount of white wine from the fire, then crisp it, repeat several times, until it is deep yellow, and let it cool; for every 10kg of hippocampus, use 2kg of white wine.

[0055] 2. Wine making (2):

[0056] A, take hip...

Embodiment 2 10

[0078] 1. Existing methods:

[0079] Wash the sediment with cold water, add 3 taels of water per catty of medicine, put it into a steel pot and cook, turn it frequently, take it out after the water is exhausted, spread it until it is 80% dry, put it into the tank, cover it with a damp cloth, moisten it thoroughly, take it out, and cut it into pieces Half-thick top slices are sun-dried.

[0080] 2. Method 1:

[0081] A, get Radix Notoginseng, pulverize to pass 80-100 mesh sieve;

[0082] B. Wash the sediment with cold water, add 3 taels of water per catty of medicine, put it into a steel pot and cook, turn it frequently, take it out after the water is exhausted, spread it until it is 80% dry, put it into the tank, cover it with a damp cloth, moisten it and take it out. Cut into half-thick top slices and dry.

[0083] 3. Method 2:

[0084] A, get Radix Notoginseng, pulverize to pass 80-100 mesh sieve;

[0085] B. Wash the sediment with cold water, add 3 taels of water per c...

Embodiment 3

[0097] Embodiment 3 Ligustrum lucidum

[0098] 1. Existing methods:

[0099] 1. Vinegar system: If the astringent effect is chosen, mix 2 taels of medicinal red vinegar per catty and absorb thoroughly, put it in a steamer and steam it until steamed, take it out and dry it in the sun.

[0100] 2. Liquor system: If it is selected to enhance the effect of nourishing the middle and nourishing yin, mix 1 tael of medicinal white wine per catty, mix well and absorb thoroughly, put it in a steamer, steam until steamed, take it out and dry it.

[0101] 2. Method 1:

[0102] 1. Vinegar:

[0103] A, get Ligustrum lucidum, pulverize to cross 80-100 mesh sieve;

[0104] B. Mix 2 taels of medicinal red vinegar per catty, mix well and absorb thoroughly, put it into a steamer and steam until steamed, take it out and dry it in the sun.

[0105] 2. Wine making:

[0106] A, get Ligustrum lucidum, pulverize to cross 80-100 mesh sieve;

[0107] B. Mix 1 tael per catty of medicinal white wine...

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Abstract

The invention which belongs to the traditional Chinese medicinal piece field concretely relates to an ultrafine traditional Chinese medicinal granule piece and a preparation process thereof. The invention which aims at present granulation processes and devices, small viscosity of traditional Chinese medicines, and the defects of irregular shape, easy moisture absorbing and bad fluidity of prepared granules provides a new production process which allows the ultrafine traditional Chinese medicinal granule piece with regular shape and good fluidity to be prepared from the small viscosity traditional Chinese medicines. The preparation process comprises the following steps: crushing the traditional Chinese medicines until the crushed traditional Chinese medicines can pass a 80-100 mesh sieve, processing according to a routine method, and crushing the traditional Chinese medicines to 400-1200 meshes; preparing a soft material; granulating by adopting a compression granulator; and drying the granules. The granule piece of the invention, which is prepared through crushing, processing and re-crushing, allows the traditional Chinese medicines to be uniformly and thoroughly processed, and the granule piece obtained through granulating and shaping the small viscosity traditional Chinese medicines by strong extruding force of the compression granulator has the advantages of regular shape, good visibility, small specific surface area, difficult moisture absorbing, and good fluidity, and can satisfy clinical medicine demands.

Description

technical field [0001] The invention belongs to the field of decoction pieces of traditional Chinese medicine, and in particular relates to decoction pieces of traditional Chinese medicine ultrafine particles and a preparation method thereof. Background technique [0002] Chinese herbal decoction pieces are Chinese medicinal materials that have been processed according to the theory of traditional Chinese medicine and the processing methods of traditional Chinese medicine, and can be directly used in Chinese medicine clinics. Decoction pieces of traditional Chinese medicine include slices of traditional Chinese medicine (including slices, blocks, and petals) processed in the place of origin, original pieces of herbal medicine, and pieces of decoction that have been cut (based on processing in the place of origin) and roasted. [0003] The inventor tried to make the traditional Chinese medicine decoction pieces into granules, but at present, the medicinal materials are usuall...

Claims

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Application Information

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IPC IPC(8): A61K36/00A61K9/16A61J3/00
Inventor 高庆凌
Owner SICHUAN JINSUIFANG PHARMA
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