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Chinese medicinal extract dripping pill for treating diabetes and hyperlipidemia

An extract and hyperlipidemia technology, applied in the field of medicine, can solve the problems of long dissolution time, low dissolution rate and bioavailability, etc., and achieve the effects of simple method, abundant raw materials and easy purchase.

Inactive Publication Date: 2012-10-03
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of the above situation, in order to solve the defects of the prior art, the object of the present invention is to provide a Chinese medicine extract drop pill for the treatment of diabetes and hyperlipidemia, which can effectively solve the long dissolution time, dissolution rate and The problem of low bioavailability

Method used

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  • Chinese medicinal extract dripping pill for treating diabetes and hyperlipidemia
  • Chinese medicinal extract dripping pill for treating diabetes and hyperlipidemia
  • Chinese medicinal extract dripping pill for treating diabetes and hyperlipidemia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The dropping pill is prepared by mixing polyethylene glycol 4000 and polyethylene glycol 6000 according to the weight ratio of 1:1 and then heating and melting to obtain the mixed base; ℃, add the extract of traditional Chinese medicine into the mixed matrix and stir evenly, then keep it warm at 75-80℃ for 20-30 minutes to obtain a molten liquid for later use; adjust the temperature control system of the dropping pill machine so that the temperature of the dripper is 76-80℃ , the temperature of the condensate is kept at 8-10°C, the above-mentioned molten liquid is placed in the liquid storage tank of the dropping pill machine, and dripped into the condensate at a rate of 20-60 drops / minute, and condensed into pellets. The weight is 35-40 mg; take out the formed dropping pills from the outlet of the dropping pill machine, and shake off the condensing agent on the surface through a dryer;

[0029] The Chinese medicine extract in the dropping pill is composed of the follow...

Embodiment 2

[0031] The dripping pill is made by mixing polyethylene glycol 4000 and polyethylene glycol 6000 according to the weight ratio of 1:3 and then heating and melting to obtain the mixed base; ℃, add the extract of traditional Chinese medicine into the mixed matrix and stir evenly, then keep it warm at 75-80℃ for 20-30 minutes to obtain a molten liquid for later use; adjust the temperature control system of the dropping pill machine so that the temperature of the dripper is 76-80℃ , the temperature of the condensate is kept at 8-10°C, the above-mentioned molten liquid is placed in the liquid storage tank of the dropping pill machine, and dripped into the condensate at a rate of 20-60 drops / minute, and condensed into pellets. The weight is 35-40 mg; take out the formed dropping pills from the outlet of the dropping pill machine, and shake off the condensing agent on the surface through a dryer;

[0032] The traditional Chinese medicine extract in the dropping pill is composed of th...

Embodiment 3

[0034] The dropping pill is made by mixing polyethylene glycol 4000 and sodium carboxymethyl starch according to the weight ratio of 1:5 and then heating and melting to obtain the mixed base; ℃, add the extract of traditional Chinese medicine into the mixed matrix and stir evenly, then keep it warm at 75-80℃ for 20-30 minutes to obtain a molten liquid for later use; adjust the temperature control system of the dropping pill machine so that the temperature of the dripper is 76-80℃ , the temperature of the condensate is kept at 8-10°C, the above-mentioned molten liquid is placed in the liquid storage tank of the dropping pill machine, and dripped into the condensate at a rate of 20-60 drops / minute, and condensed into pellets. The weight is 35-40 mg; take out the formed dropping pills from the outlet of the dropping pill machine, and shake off the condensing agent on the surface through a dryer;

[0035] The Chinese medicine extract in the dropping pill is composed of the followi...

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Abstract

The invention relates to a Chinese medicinal extract dripping pill for treating diabetes and hyperlipidemia, which can effectively solve the problems of long dissolving time, low dissolubility and bio-availability of existing Chinese medicinal oral preparations after administration. A technical proposal provided by the invention comprises the steps of mixing polyethylene glycol (PEG) 4000 and PEG6000, or PEG 4000 and sodium carboxymethyl starch or Poloxamer, or PEG 6000 and sodium carboxymethyl starch or Poloxamer at weight ratio of 1:(1-10), and heating and melting to obtain matrix; mixing 10-30 wt% of Fructus Rosae Laevigatae extract, 5-25 wt% of Fructus Mori extract, 10-30 wt% of Rhizoma Coptidis extract, 5-20 wt% of Radix Astragali extract, 5-20 wt% of Polygoni Multiflori Radix extract, and 5-20 wt% of Fructus Corni extract, wherein the total amount of the Chinese medicinal extracts is 100%; and mixing the Chinese medicinal extracts with the matrix at weight ratio of 1:(1.5-5). The inventive dripping pill has the advantages of abundant and easily-accessible materials, simple production, and good treatment effect, and is an innovation in aspect of medicines for treating diabetes and hyperlipidemia.

Description

technical field [0001] The invention relates to medicine, in particular to a traditional Chinese medicine extract drop pill for treating diabetes and hyperlipidemia. Background technique [0002] With the improvement of people's living standards, most of the diet is too greasy, and the sugar content in the food has also increased, which has caused the incidence of diabetes to increase year by year. At present, more and more people are aware of the seriousness of diabetes and begin to pay attention to diabetes. , the patient is actively seeking treatment. Diabetes is caused by genetic factors, immune dysfunction, microbial infection and its toxins, free radical toxins, mental factors and other pathogenic factors acting on the body to cause hypofunction of pancreatic islets and insulin resistance. , protein, fat, water and electrolytes and a series of metabolic disorder syndromes, clinically characterized by hyperglycemia, polyuria, polydipsia, polyphagia, weight loss and othe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/738A61K9/20A61K47/34A61K9/36A61P3/06A61P3/10
Inventor 李玉贤褚意新万焱
Owner HENAN UNIV OF CHINESE MEDICINE
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