Biological bactericide chelerythrine suspending agent and preparation method thereof
A technology of chelerythrine and biological fungicide, which is applied in the field of chelerythrine suspension and its preparation, can solve the problems of no new fixed point, less research on dosage forms, lag, etc.
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Embodiment 1
[0011] [Example 1] 0.3% chelerythrine suspension concentrate
[0012] Chelidonine 0.3-0.5kg Sodium lignosulfonate 4-6kg Sodium dodecylbenzenesulfonate 7-10kg
[0013] Xanthan gum 0.1-0.3kg Ethylene glycol 1-3kg Silicone 0.1-0.3kg
[0014] Potassium dihydrogen phosphate 1-3kg Water 80-90kg
[0015] The preferred dosage is
[0016] Chelidonine 0.3kg Sodium lignosulfonate 5kg Sodium dodecylbenzenesulfonate 8kg
[0017] Xanthan Gum 0.2kg Ethylene Glycol 2kg Silicone 0.2kg
[0018] Potassium dihydrogen phosphate 2kg Water 82.3kg
[0019] Preparation
[0020] 1. Add sodium lignosulfonate, sodium dodecylbenzenesulfonate and ethylene glycol into the container according to the weight of the above components, then slowly add water into the container and stir. Add metered chelerythrine parent drug, silicone, xanthan gum and potassium dihydrogen phosphate in sequence under high-speed shear force stirring.
[0021] 2. Pour the above materials into a sand mill for grinding until the ...
Embodiment 2
[0022] [Example 2] Concentration content is 5% chelerythrine suspension concentrate
[0023] Chelidonine 5kg Sodium Alkylphenol Polyoxyethylene Phosphate 8kg
[0024] Calcium Alkenyl Carboxylate 10kg Magnesium Aluminum Silicate 0.5kg
[0025] Urea 2kg Polyglycerol 0.4kg
[0026] Ammonia 1.5kg Water 72.6kg
[0027] Preparation
[0028] Add the sodium alkylphenol polyoxyethylene phosphate, calcium alkenyl carboxylate and urea into the container according to the weight of the above components, then slowly add water into the container and stir. Add metered chelerythrine technical substance, polyglycerol, magnesium aluminum silicate and ammonia water sequentially under high-speed shear force stirring. Pour the above materials into a sand mill for grinding until the average fineness is 2-4 μm, and finally form a suspending agent. According to the quality control index of the suspension, the product quality inspection of the active ingredient, pH value, wet sieve test, suspensio...
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