Application of desloratadine compound in preparing information medicine, preparation method and prepared novel drug

Abstract

The invention discloses application of a desloratadine compound in preparing an information medicine, a preparation method of the information medicine by the desloratadine compound and a novel drug prepared by the preparation method. During the treatment, the information medicine does not directly touch a human body, drug substance components are not consumed, chemotherapy effects can be achieved only by utilizing drug information physiotherapy, and the therapy window is enlarged by more than one thousand times, and side effects of the chemotherapy are avoided. After desloratadine is used as the information treatment drug, the effective component content is not changed, and desloratadine can be used secondarily and effectively as a chemotherapy normal preparation.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a novel drug of desloratadine. Background technique [0002] Compound desloratadine (Desloratadine), chemical name: 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]arhepta[1,2 -b] pyridine, chemical formula C 19 h 19 ClN 2 , molecular weight 310.82. Appearance is white crystalline powder. Desloratadine is an antiallergic drug, clinically used for the treatment of allergic diseases. The pharmaceutical preparations of desloratadine include tablets, capsules and the like. The known desloratadine drugs are all used as chemotherapeutic drugs, which allow the compound desloratadine molecules to enter the human body (through oral absorption into the blood), distribute to various tissues, and produce chemical reactions through the drug molecules in the human body. pharmacological effects. In the prior art, desloratadine has insurmountable defects as a chemotherapeutic drug, th...

AI Technical Summary

Problems solved by technology

In the prior art, desloratadine has insurmountable defects as a chemotherapeutic drug, the first is the toxic and side effects on the human body, and its unpleasant adverse reactions include dry mouth, tiredness, headache, nausea, lethargy , forgetfulness, edema, heartbeat, tachycardia, palpitations, elevated liver enzymes, increased bilirubin, etc.; second, the treatment window is small. Due to the toxic and side effects on the human body, the effective dose that can be used is very small, which limits the therapeutic effect. The maximum dose of oral administration is 5 mg once and 5 mg per day. If the maximum dose is exceeded, it can cause poisoning; the third is that there is only one use of chemotherapy drugs, and the drugs will be metabolized or excreted when they enter the human body, so they cannot be used for the second time.

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