X-ray coaxial phase-contrast imaging method

Abstract

The invention belongs to the fields of biomedical engineering and medical imaging, relating to an X-ray coaxial phase-contrast imaging method, which comprises the steps of: placing a knife edge device to be appressed onto the surface of a detector, and continuously acquiring n frames of images to obtain a corresponding detector transfer function curve; transforming to obtain a detector transfer function matrix; placing an imaging object and imaging the object; establishing a phase-contrast imaging deterioration model in a matrix manner; selecting a regularization matrix according to the coaxial phase-contrast imaging result of the object and the detector transfer function matrix, and acquiring an optimal regularization parameter corresponding to the regularization matrix by using an L curve method; and calculating a numerical solution of regularization image recovery, of the coaxial phase-contrast imaging result. The X-ray coaxial phase-contrast imaging method disclosed by the invention can be used for effectively increasing the contrast of a phase-contrast image under a deterioration effect and guaranteeing the fidelity of a recovered image.

Description

technical field [0001] The invention belongs to the fields of biomedical engineering and medical imaging, and relates to an X-ray coaxial phase contrast imaging method. Background technique [0002] Breast cancer is currently the number one "killer" of women. According to the statistics of the World Health Organization, in 2000, about 1.2 million women in the world were diagnosed with breast cancer, and 500,000 people died of breast cancer. Breast cancer not only endangers the lives of patients, but also causes damage to female sexual organs, seriously endangering women's physical and mental health. Although China is not a country with a high incidence of breast cancer, its average annual growth rate has been 1-2 percentage points higher than that of high-incidence countries in the past ten years, with an annual growth rate of 3%-4%. Due to the large population in our country, the diagnosis and treatment of breast cancer has become an increasingly serious social problem tha...

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Problems solved by technology

[0010] The gist of the present invention is to propose an imaging method capable of improving the quality of X-ray coaxial phase contrast imaging, so as to solve the key problems faced by coaxial phase contrast imaging under current engineering conditions: due to the current engineering conditions, microfocus X The non-ideality of the light source, the detector and the system noise cause the deterioration of the phase contrast image quality and the reduction of the phase contrast

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