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Compound Siberian solomonseal rhizome preparation capable of improving vigor of superoxide dismutase

A technology of superoxide and dismutase, which can be used in medical preparations containing active ingredients, antidote, food science, etc., and can solve problems such as side effects

Inactive Publication Date: 2012-06-27
SHANDONG UNIV AT WEIHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Synthetic antioxidants have good antioxidant properties, but they have certain side effects

Method used

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  • Compound Siberian solomonseal rhizome preparation capable of improving vigor of superoxide dismutase
  • Compound Siberian solomonseal rhizome preparation capable of improving vigor of superoxide dismutase

Examples

Experimental program
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Effect test

Embodiment 1

[0019] 1, a kind of preparation method that is to be able to improve the compound Polygonatum preparation of superoxide dismutase activity, is characterized in that comprising the following steps:

[0020] (1) The weight ratio of raw materials is: Polygonatum 9g, Atractylodes macrocephala 6g, Porphyridum 10g;

[0021] (2) Add 8 times the amount of Polygonatum and Atractylodes Rhizoma Atractylodes Rhizome to 70% ethanol to extract 8 times at room temperature, then seal and sonicate for 30 minutes at a temperature of 30°C and a power of 80W, then filter with gauze, and use 6 times and 4 times the amount of filter residues respectively Repeat the extraction with 70% ethanol once, filter to obtain the filtrate;

[0022] (3) The filtrates in (2) are combined, ethanol is reclaimed, and the extracts of Rhizoma Polygonatum and Atractylodes Rhizoma Rhizome are obtained;

[0023] (4) Centrifuge Porphyridium algae with a 5000r / min centrifuge for 10min, then suspend it in pH 7.4, 50mmol / ...

Embodiment 2

[0027] 1, a kind of preparation method that is to be able to improve the compound Polygonatum preparation of superoxide dismutase activity, is characterized in that comprising the following steps:

[0028] (1) The weight ratio of raw materials is: Polygonatum 12g, Atractylodes macrocephala 9g, Porphyridum 20g;

[0029] (2) Add 10 times the amount of Polygonatum and Atractylodes Rhizoma Rhizome to 70% ethanol to extract at room temperature for 10 hours, then seal and ultrasonicate for 30 minutes at a temperature of 30°C and a power of 80W, then filter with gauze, and use 6 times and 4 times the amount of filter residues respectively Repeat the extraction with 70% ethanol once, filter to obtain the filtrate;

[0030] (3) The filtrates in (2) are combined, ethanol is reclaimed, and the extracts of Rhizoma Polygonatum and Atractylodes Rhizoma Rhizome are obtained;

[0031] (4) Centrifuge Porphyridium algae with a 5000r / min centrifuge for 10min, then suspend it in pH 7.4, 50mmol / L...

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Abstract

The invention belongs to the technical field of processing of health-care food, and relates to a compound Siberian solomonseal rhizome preparation capable of improving the vigor of superoxide dismutase. A method for preparing the compound Siberian solomonseal rhizome preparation comprises the following steps of: adding 70 percent ethanol in an amount which is 10 times that of 12 grams of Siberian solomonseal rhizome and 9 grams of largehead atractylodes rhizome, leaching at room temperature for 10 hours, performing hermetic ultrasound for 30 minutes, filtering, extracting filter residues once again from 70 percent ethanol in an amount which is 6 times and 4 times that of the filter residues respectively; mixing the filtrate, and recovering the ethanol to obtain a Siberian solomonseal rhizome extract and a largehead atractylodes rhizome extract; centrifuging 20 grams of porphyridium cruentum for 10 minutes by using a centrifugal machine, suspending in 50 mmol / L of phosphate buffer, of which the pH value is 7.4, performing ultrasonication, centrifuging for 15 minutes by using a high-speed freezing centrifugal machine to obtain supernate, and freezing and drying to obtain a dry substance; and mixing the dry substance with the Siberian solomonseal rhizome extract and the largehead atractylodes rhizome extract uniformly to obtain the compound Siberian solomonseal rhizome preparation. The compound Siberian solomonseal rhizome preparation can be used for developing new natural antioxidants in fields of food, medicines and the like and is favorable for industrial production.

Description

technical field [0001] The invention belongs to the technical field of health food processing, and the invention relates to a compound Polygonatum preparation capable of improving the activity of superoxide dismutase. The product of the invention can be used to develop new natural antioxidants in the fields of food, medicine and the like, and the product of the invention is beneficial to industrial production. Background technique [0002] Polygonatum is the dried rhizome of Polygonatum kingianum Coll. et Hemsl., Polygonatum sibiricum Red. or Polygonatum cyrtonema Hua. Gan, flat. Return lung, spleen, kidney channel. Nourishes the kidneys and moistens the lungs, invigorates the spleen and qi. Polygonatum rhizome contains saponins, niacin, mucus, quinones. It also contains Polygonatum polysaccharides A, B, and C, and Polygonatum oligosaccharides A, B, and C. Polysaccharides A, B, and C are composed of glucose, mannose, and galacturaldehyde Acid combined; oligosaccharides A...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P39/06A23L1/29A23L33/00
Inventor 张崇禧侯欣池张成城郑友兰
Owner SHANDONG UNIV AT WEIHAI
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