Neural microelectrode with rigid and flexible structures

Abstract

The invention relates to a neural microelectrode with rigid and flexible structures. The microelectrode comprises a rigid structure part and a flexible structure part, wherein the geometric structure of the electrode is improved and a flexible material coating is coated on the surface of the electrode; the flexible structure part can completely replace the rigid structure part or penetrates through the rigid structure part or is attached to the rigid structure; the rigid material is silicon or other ceramic materials; the flexible material is polyimide, benzocyclobutene, SU-8, polydimethyl siloxane and poly-p-xylene; the method for improving the geometric shape of the electrode mainly comprises the step of reducing the sectional area of the electrode; a layer of flexible material coating is deposited on the surface of the electrode; and the flexible coating material is conductive hydrogel, mucoprotein and polyethyleneimine. According to the invention, the flexibility of the improved microelectrode is effectively improved, the injury of jiggle to biological tissues is alleviated, which is beneficial to the long-term in-vivo indwelling of the electrode.

Description

technical field [0001] The invention relates to biomedical engineering, in particular to a microelectrode with a rigid-flexible structure for nerves. Background technique [0002] The nervous system is an open and complex giant system, and the in-depth study of the nervous system is the most challenging exploration for human beings. For centuries, human beings have been trying to explore the mysteries of the nervous system and seek effective means to treat neurological diseases. With the deepening of people's research on neuroscience, the discipline of neuroengineering has been derived. It is an interdisciplinary subject of neuroscience, material science, microelectronics technology and information science. Neurorehabilitation and other aspects are of great significance. Neuroprosthetic devices, such as deep brain stimulators, use neuromicroelectrodes as the interface between the nervous system and external devices. Deep Brain Stimulation, a neurosurgical treatment in whi...

AI Technical Summary

Problems solved by technology

The microelectrode prepared by this method, although the low Young's elastic modulus of the polymer material can improve the flexibility of the microelectrode, which is conducive to the adhesion of the microelectrode to the surface of biological tissue, but it is not conducive to the microelectrode because it is too soft. surgical implant

In addition, this article only considers how to improve the flexibility of the microelectrodes from the perspective of materials, and does not propose a suitable improvement plan for improving the flexibility of the microelectrodes in terms of the geometric structure of the microelectrodes.

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