Preparation technology for compound aquatic organism collagen peptide-calcium complex, technology for preparing calcium supplement from complex, and application of calcium supplement

Abstract

The invention relates to a preparation technology for an aquatic organism collagen peptide-calcium complex. The preparation technology comprises the following steps: 1, hydrolyzing raw materials of processed natural fish scales and fish skins by an inorganic acid or an organic acid to prepare a collagen peptide hydrolysate; 2, removing the sediment from the collagen peptide hydrolysate, carrying out depickling, separating purification and desalination concentration on the obtained supernatant to obtain a collagen peptide hydrolysate with the molecular weight of 1-20KDa; and 3, adjusting the pH value of the collagen peptide hydrolysate to 6-8, adding a calcium salt with the metal element calcium mole content equal to the mole content of amino nitrogen in the hydrolysate, and removing free metal element calcium and the inorganic salt which are uncomplexed from the obtained reaction liquid to obtain the liquid collagen peptide-calcium complex. The complex is added with vitamin D3 and ascorbic acid to prepare a compound aquatic organism collagen peptide-calcium supplement. The calcium supplement which can be used as a medicine for preventing and controlling diseases with symptoms of osteoporosis and the like and a functional health food can also be used as a safe high efficiency calcium nutriment and a vitamin D3 and ascorbic acid supplement.

Description

technical field [0001] The present invention relates to the technical field of health food or medicine, especially a preparation process for preparing aquatic collagen peptide calcium coordination compound by chelating or complexing aquatic collagen peptide and metal element calcium, and a compound aquatic collagen peptide calcium supplement Preparation process, and the application of the calcium supplement in health food and medicine. Background technique [0002] Calcium is the most abundant mineral element necessary for the human body, accounting for 1.5-2.0% of the body weight, and it undertakes important physiological functions in the body. However, the dietary pattern of Chinese people is mainly based on cereals, and the calcium intake is generally low, only reaching about 50% of the recommended amount, and due to the difference in the human body's ability to absorb calcium, the calcium absorption rate is low. Calcium deficiency is a common nutritional problem. From i...

AI Technical Summary

Problems solved by technology

[0003] The calcium supplements currently used clinically, the first generation is calcium carbonate, and the second generation is organic acid calcium, both of which are ionized calcium, with poor stability, many factors affecting absorption, low bioavailability, large side effects, and insufficient absorption rate. 40%; the third generation is amino acid chelated calcium. Calcium can use free amino acids as a carrier. The entire molecule of calcium and its organic groups is completely absorbed by the intestinal tract, which belongs to the unsaturated absorption process, avoids the generation of hypercalcemia, and has anti It has the advantages of strong interference, good stability, and easy absorption, but its production cost is high, which greatly limits its application; the fourth generation is small peptide chelated calcium, which is developed on the basis of the third generation of calcium supplements. The body's unique absorption system for small peptides promotes the absorption of calcium. Compared with amino acid chelated calcium, it has the advantages of fast absorption, less saturation, and low energy consumption.

At present, most small peptide chelated calcium products have a peptide molecular weight greater than 10KDa, and some products simply mix the peptide with ionized calcium, and do not form a true peptide calcium coordination compound.

In addition, vitamin D3 and ascorbic acid, which are good at promoting calcium absorption, are mostly only used in the first and second generation calcium supplements, and are rarely used in the fourth generation products.