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Application of medicinal composition to preparation of medicaments for treating duodenal ulcer

A technology for duodenal ulcer and composition, which is applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of long healing time, high price, and large side effects, etc., and achieve good gastric mucosa repair effect and pain relief good effect

Inactive Publication Date: 2012-04-18
成都酷妃儿商贸有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The current medicines for treating the above diseases are mostly chemical medicines, which are expensive, have large side effects, and take a long time to cure

Method used

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  • Application of medicinal composition to preparation of medicaments for treating duodenal ulcer
  • Application of medicinal composition to preparation of medicaments for treating duodenal ulcer

Examples

Experimental program
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Effect test

Embodiment 1

[0025] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0026] Take 20g coix seed, 20g wax gourd kernel, 15g capillary, 15g Atractylodes macrocephala, 10g perilla leaf, 10g bitter almond, 10g white lentil, 10g nutmeg, 10g astragalus, 5g ginseng, 5g forsythia; first add 4 times the amount of water to soak After 10 minutes, decoct with water for 2 times, each time for 20 minutes, add 10 times the amount of water each time, filter, and combine the decoctions to obtain the pharmaceutical composition decoction of the present invention.

Embodiment 2

[0027] The preparation of embodiment 2 pharmaceutical compositions of the present invention

[0028] Coix seed 14g, winter melon kernel 26g, capillary wormwood 19.5g, Atractylodes macrocephala 19.5g, perilla leaf 13g, bitter almond 13g, white lentil 13g, nutmeg 13g, astragalus 13g, ginseng 6.5g, forsythia 6.5g; The first time, add 10 times the amount of water to decoct for 5 minutes, the second time add 8 times the amount of water to decoct for 10 minutes, the third time add 8 times the amount of water to decoct for 15 minutes, filter, combine the decoction, and concentrate , then add appropriate starch and granulate to obtain the pharmaceutical composition granules of the present invention.

Embodiment 3

[0029] The preparation of embodiment 3 pharmaceutical compositions of the present invention

[0030] Take 3.5g of ginseng, crush it, pass through a 80-mesh sieve, and use ginseng powder for later use; take 26g of coix seed, 14g of winter melon kernel, 10.5g of capillary root, 10.5g of Atractylodes macrocephala, 7g of perilla leaf, 7g of bitter almond, 7g of white lentil, and 7g of nutmeg , astragalus 7g, forsythia 3.5g; first add 10 times the amount of 70% ethanol solution to reflux for extraction once, extract for 1 hour, filter, the filtrate is set aside, and the filter residue is decocted twice with water, adding 8 times the amount of water each time, decocting each time Boil for 20 minutes, combine the ethanol extract and water decoction, concentrate, then add appropriate amount of microcrystalline cellulose, dextrin and ginseng powder, after granulation, add appropriate amount of magnesium stearate, and press into tablets to obtain the drug of the present invention Compos...

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Abstract

The invention discloses application of a medicinal composition to the preparation of medicaments for treating duodenal ulcer. The medicinal composition is prepared from the following Chinese herbal medicines in part by weight: 14 to 26 parts of coix seed, 14 to 26 parts of wax gourd seed, 10.5 to 19.5 parts of virgate wormwood herb, 10.5 to 19.5 parts of largehead atractylodes rhizome, 7 to 13 parts of perilla leaf, 7 to 13 parts of bitter apricot seed, 7 to 13 parts of white hyacinth bean, 7 to 13 parts of semen myristicae, 7 to 13 parts of astragalus, 3.5 to 6.5 parts of ginseng and 3.5 to 6.5 parts of weeping forsythia. The medicinal composition exerts a synergistic effect after reasonable compatibility, can treat gastric ulcer, duodenal ulcer and erosive gastritis effectively, has thegood effects of relieving pain and repair gastric mucosa, and provides a new choice for clinical administration.

Description

technical field [0001] The invention relates to the application of a pharmaceutical composition in the preparation of medicine for treating duodenal ulcer. Background technique [0002] Gastric and duodenal ulcers refer to localized round or oval full-thickness defects of gastric and duodenal mucosa, the muscularis mucosae is penetrated, and fibrous scars inevitably remain after healing, with a layer of epithelium on the surface covered, the muscularis mucosa cannot regenerate. The etiology can be summed up as the self-digestion of gastric mucosa by gastric acid and pepsin or the destruction of gastric mucosal barrier due to various reasons. In recent years, it has been considered that the formation of ulcers has an important relationship with Helicobacter pylori infection in the stomach. [0003] Chronic erosive gastritis, also known as verrucous gastritis or pimple-like gastritis, generally only sees dyspepsia symptoms such as fullness after meals, pantothenic acid, belc...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P1/04
Inventor 董青昌许婧杨婷安静易凤敏任朝琴
Owner 成都酷妃儿商贸有限公司
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