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Broad-spectrum and high-efficiency antibacterial washing liquor

A lotion, high-efficiency technology, applied in the direction of antibacterial drugs, antifungal agents, local antibacterial agents, etc., can solve the problems of inability to really kill pathogenic microorganisms and limited use effect

Inactive Publication Date: 2012-04-18
艾硕特生物科技(昆明)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Most lotions currently on the market are antibacterial lotions, which cannot really kill pathogenic microorganisms, but can only inhibit the growth of pathogenic microorganisms, and their use effect is limited

Method used

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  • Broad-spectrum and high-efficiency antibacterial washing liquor
  • Broad-spectrum and high-efficiency antibacterial washing liquor
  • Broad-spectrum and high-efficiency antibacterial washing liquor

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0070] The preparation method of antibacterial lotion of the present invention

[0071] The preparation of antibacterial lotion of the present invention comprises the steps:

[0072] ①. Take the following raw materials according to the weight ratio, mix them evenly, and prepare a homogeneous solution at 30°C:

[0073] N-coconut oil fatty acid acyl L-arginine ethyl ester DL-pyrrolidone carboxylate: 0.0001-2.0,

[0074] Lauryl dimethyl benzyl ammonium chloride: 0.0001-1.0,

[0075] Water: 10.0-99.995.

[0076] ②. If you want to add myristyl dimethyl amine oxide and aloe vera gel to the antibacterial lotion, you only need to take the following raw materials according to the weight ratio, add them to the above mixture, mix and stir to form a colorless transparent liquid:

[0077] Myristyl dimethylamine oxide: 0.001-3.0,

[0078] Sodium chloride: 0.00001-1.0,

[0079] Malic acid: 0.0001-0.1.

[0080] ③. Use a filling machine to pack into suitable containers to obtain finished...

Embodiment 1

[0086] Embodiment 1. the preparation of antibacterial lotion of the present invention

[0087] 1. The raw materials of 36 formulas and their weight proportions are listed in table 1. For each formula, the raw materials are selected according to the weight ratio, and a homogeneous solution or a colorless transparent water-soluble solution is obtained according to the above-mentioned preparation method.

[0088] Table 1. Raw materials and weight ratio (kg) of the formula

[0089]

[0090] Note: NaCl = sodium chloride; C1 = myristyl dimethylamine oxide; DH 2 O = deionized, distilled or purified water; C3 = N-coconut fatty acid acyl L-arginine ethyl ester DL-pyrrolidone carboxylate; M1 = dodecyldimethylbenzyl ammonium chloride; MA = malic acid.

[0091] Below take formula 1 as example to further illustrate the preparation method of this antibacterial lotion solution:

[0092] ①. Mix 0.1Kg N-coconut oil fatty acid acyl L-arginine ethyl ester DL-pyrrolidone carboxylate and 0....

Embodiment 2

[0095] Embodiment 2. The effectiveness detection of antibacterial lotion of the present invention to kill Ureaplasma urealyticum

[0096] ①.Main material

[0097] A. Test strain: Ureaplasma Urealyticum (Ureaplasma Urealyticum) international standard passage strain;

[0098] B. Culture medium: high-efficiency mycoplasma liquid medium;

[0099] C. Test sample: the antibacterial lotion prepared by embodiment 1 (formulation 1).

[0100] ②. Test basis and method

[0101] Test basis: Ministry of Health "Disinfection Technical Specifications" (2002 Edition) Part II "Disinfectant Microbicide Experiment" method and operating procedures, combined with laboratory diagnosis of sexually transmitted diseases (2001) Chapter thirteen, four.

[0102] Test method: according to the standard operating procedure stipulated in the work instruction NCSTD-JX15-2008.

[0103] Experimental temperature: 25℃~28℃.

[0104] ③.Test results

[0105] Table 8. The killing effect of test samples on Ureapl...

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Abstract

The invention relates to a medicine, in particular to broad-spectrum and high-efficiency antibacterial washing liquor and a preparation method thereof. The invention is characterized in that the antibacterial washing liquor is prepared by the following materials according to the weight ratio: 0.0001-2.0 of N-coconut-oil fatty-acid acyl L-arginine ethyl ester DL-pyrrolidone carboxylate, 0.0001-1.0 of dodecyl dimethyl benzyl ammonium chloride, 10.0-99.995 of water, and the balance of auxiliary materials. The broad-spectrum and high-efficiency antibacterial washing liquor has the following characteristics and advantages that pathogenic microorganisms are killed in a broad-spectrum and high-efficiency manner; ureaplasma urealytium, gonococcocci and trichomonas vaginalis can be killed in one minute; the killing rate for escherichia coli, staphylococcus aureus and candida albicans is respectively more than 99%; non-toxic; no stimulation is caused to the skin; no allergic reaction is caused; no stimulation is caused to the eyes; no stimulation is caused to vaginal mucosa; and the pH value of a preparation is close to that in the normal vagina.

Description

technical field [0001] The invention relates to a medicine, in particular to a broad-spectrum, high-efficiency antibacterial lotion and a preparation method thereof. Background technique [0002] The rapid development of society has greatly improved people's living standards. Women pay more and more attention to the health of their reproductive tract, and often use some care products to clean the reproductive tract. Reproductive tract infection is also a frequently-occurring disease and a common disease in women. There are many medicines for treating such diseases in the market, and lotion is a class of preparations that are more accepted by women. [0003] Most lotions currently on the market are antibacterial lotions, which cannot really kill pathogenic microorganisms, but can only inhibit the growth of pathogenic microorganisms, and their use effect is limited. In view of the patent (a broad-spectrum, high-efficiency microbial killer; patent number: ZL 200710066058.6) t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/40A61K31/223A61P15/02A61P17/00A61P31/02A61P31/04A61P31/10A61P33/02A01N47/44A01N43/36A01P1/00A01P3/00
CPCY02A50/30
Inventor 陆可望张磊
Owner 艾硕特生物科技(昆明)有限公司
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