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Method for preparing cardiac medicament eluting stent with deer blood

A heart and drug technology, applied in medical science, surgery, etc., can solve problems such as delayed endothelialization, achieve the effects of inhibiting smooth muscle hyperplasia and migration, accelerating the process of endothelialization, and strong anti-inflammatory effects

Inactive Publication Date: 2012-04-04
苏州红冠庄国药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The drugs currently on the market for coated degradable stents are still rapamycin or paclitaxel, both of which can inhibit the proliferation and migration of vascular smooth muscle cells, so drug-coated stents can reduce in-stent restenosis , but at the same time, these two drugs also inhibit the growth of endothelial cells, resulting in delayed endothelialization, which can easily lead to the formation of late thrombus in the stent

Method used

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Embodiment Construction

[0006] The invention discloses a method for preparing a heart drug stent from deer blood. The deer blood is poured into a heart drug stent mold, left to dry, and the product is obtained after drying.

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PUM

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Abstract

The invention discloses a method for preparing a cardiac medicament eluting stent with deer blood. The method comprises the following steps of: pouring deer blood into a cardiac medicament eluting stent mold; and standing and drying to obtain the product. The cardiac medicament eluting stent prepared by using the method can be degraded completely, and can be used for suppressing the hyperplasia and translation of smooth muscle cells, promoting the growth of endothelial cells and accelerating endothelialization.

Description

technical field [0001] The invention relates to a method for preparing a heart drug stent by using deer blood. Background technique [0002] In recent years, percutaneous coronary intervention (PCI) has surpassed percutaneous transluminal coronary angioplasty (GABC) and has become the most commonly used procedure for the treatment of coronary artery disease. Since Gruentzig completed the world's first percutaneous transluminal coronary angioplasty (PTCA) in Zurich, Switzerland in 1977, it ushered in a new era of interventional heart disease treatment. Intracoronary bare metal stent (BMS, 1985) and drug-eluting stent (DES, 2003) placed two historic leaps. However, although the probability of in-stent restenosis after using drug-eluting stents is significantly lower than that of bare metal stents, the problem of restenosis has not been fundamentally resolved. Delayed, stent thrombosis. In view of this, a new type of biodegradable coated stent has emerged as the times requir...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/16A61L31/04
Inventor 葛均波沈俊逸杨彦鹏周翠霞
Owner 苏州红冠庄国药股份有限公司
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