Application of mussel agglutinin to preparation of cosmetics
A technology for mussel lectin and cosmetics, which is applied to the application field of mussel lectin in the preparation of cosmetics, and achieves the effects of preventing ultraviolet light damage, simple and mature preparation process and easy source.
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Embodiment 1
[0009] Determination of growth-promoting activity of skin cream containing mussel agglutinin (CGL) on fibroblasts:
[0010] 1. Sample Preparation
[0011] N-acetylgalactosamine / galactose (GalNAc / Gal)-specific mussel lectin (CGL) according to Li Wei, Xiong Chuannan and Wang Jianhua et al. in "Journal of Shenyang Agricultural University", 2007, Vol. 38, No. 2 It was prepared by the method described in "Studies on the Anti-HIV Activity of Mussel Lectin" published on pages 207-210 of the issue.
[0012] Skin care cream is formula shown in table 1:
[0013] Table 1
[0014] Element mass percentage Element mass percentage Glyceryl monostearate 8 Propylparaben 0.5 stearic acid 8 Glycerol 10 cetyl alcohol 1 Triethanolamine 1 Propyl paraben 0.1 distilled water 69.9 Simethicone 1 essence 0.5
[0015] (1) Sample preparation of skin cream containing lectin: According to Table 1, the oil-phase raw materials and oil-solubl...
Embodiment 2
[0028] Determination of protective activity of mussel lectin (CGL)-containing skin cream against UV damage in fibroblasts:
[0029] 1. Sample Preparation:
[0030] The preparation methods of mussel lectin (CGL) and skin cream are the same as in Example 1.
[0031] (1) Sample preparation of lectin-containing skin cream: sample preparation of lectin-containing skin cream: mix the oil-phase raw materials and oil-soluble emulsifier according to the above table, mix and heat to 80°C under constant stirring, and maintain for 20 minutes to sterilize , add the water phase raw materials and water-soluble emulsifier to distilled water, heat to 80°C under stirring, maintain 20min for sterilization, and then cool down, add mussel agglutinin (CGL) with a mass ratio of 1 / 10,000 to the skin cream Slowly add to the water phase to stir and emulsify, then add the water phase to the oil phase, add the essence when the temperature drops to 45°C, continue to stir and cool, and then the skin crea...
Embodiment 3
[0044] Examples 1 and 2 respectively show that N-acetylgalactosamine / galactose (GalNAc / Gal)-specific mussel agglutinin (CGL) can significantly promote the growth of fibroblasts and protect fibroblasts from ultraviolet damage . For this purpose, N-acetylgalactosamine / galactose (GalNAc / Gal) specific mussel agglutinin (CGL) can be added to Among the basic raw materials of existing cosmetics, it can be made into skin cream, eye cream, barrier cream, hand cream and massage cream, etc., which can be applied to the skin to prevent skin damage caused by ultraviolet rays.
[0045] Prepare hand cream according to the formula ratio shown in table 4:
[0046] Table 4
[0047]
[0048]According to Table 4, mix and heat the oil phase raw materials and oil-soluble emulsifier to 80°C under constant stirring, maintain for 20 minutes for sterilization, add the water phase raw materials and water-soluble emulsifier into distilled water, and heat to 80°C while stirring. Keep it sterilized f...
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