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Chinese medicinal composition for treating chloasma, preparation method and application thereof

A technology for chloasma and a composition is applied in the directions of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve the problems of deepening chloasma, inability to eradicate chloasma, toxic and side effects, and the like, and achieve inhibition of melanin pigmentation. , Pigmentation reduction, the effect of inhibiting tyrosinase activity

Inactive Publication Date: 2012-02-01
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But it can only control, not eradicate chloasma
Commonly used topical external medicines include hydroquinone, azelaic acid, tretinoin, kojic acid, and chemical peeling agent external preparations, but these chemicals are prone to serious toxic and side effects, and even deepen chloasma. The market is in urgent need of an effective, Has been proven by most people to treat chloasma Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1: Take 40g of Bletilla striata and 10g of Angelica dahurica in proportion, add water, decoct twice, add water for the first time to 8 times the weight of the medicinal materials, decoct for 1 hour, add water for the second time to 6 times the weight of the medicinal materials decoct for 1 hour, combine the decoction, filter, and concentrate the filtrate to 65°C to measure the extract with a relative density of 1.05; weigh 3g of Mituseng, 3g of pearl powder, 3g of bitter almond and 1g of borneol, and crush them into fine Powder, passed through a 100-mesh sieve; Weigh 45g of stearic acid, 26g of glyceryl monostearate, 27g of white petrolatum and 80g of liquid paraffin, heat and stir in a water bath until fully melted to make the oil phase, and mix Mitus, pearl Fine powder, bitter almonds and borneol are put into the oil phase and stirred evenly, and kept warm at 70-80°C; another appropriate amount of glycerin 53g, triethanolamine 5g, sodium lauryl sulfate 1g, and ...

Embodiment 2

[0027] Example 2: Take 30 g of Bletilla striata and 20 g of Angelica dahurica in proportion, add water, decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 1.5 hours, add water for the second time to 8 times the weight of the medicinal materials Double the amount, decoct for 1.5h, combine the decoction, filter, and concentrate the filtrate to 65°C to measure the extract with a relative density of 1.10; weigh 2g of Mituseng, 5g of pearl powder, 2g of bitter almond and 2g of borneol, and crush them into a fine powder and pass through a 100-mesh sieve; weigh 45g of stearic acid, 26g of glyceryl monostearate, 27g of white petrolatum and 80g of liquid paraffin, heat and stir in a water bath until fully melted to make an oil phase, and mix , fine powder of pearl powder, bitter almond and borneol, put into the oil phase and stir evenly, keep warm at 70-80°C; take another appropriate amount of glycerin 53g, triethanolamine 5g, sodium...

Embodiment 3

[0028] Example 3: Take 20g of Bletilla striata and 30g of Angelica dahurica in proportion, add water, decoct twice, add water for the first time to be 12 times the weight of the medicinal materials, decoct for 2 hours, add water for the second time to be 10 times the weight of the medicinal materials decoct for 2 hours, combine the decoction, filter, and concentrate the filtrate to 65°C to measure the extract with a relative density of 1.10; weigh 1g of Mituseng, 7g of pearl powder, 1g of bitter almond and 3g of borneol, and crush them into fine Powder, passed through a 100-mesh sieve; Weigh 45g of stearic acid, 26g of glyceryl monostearate, 27g of white petrolatum and 80g of liquid paraffin, heat and stir in a water bath until fully melted to make the oil phase, and mix Mitus, pearl Fine powder, bitter almonds and borneol are put into the oil phase and stirred evenly, and kept warm at 70-80°C; another appropriate amount of glycerin 53g, triethanolamine 5g, sodium lauryl sulfat...

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PUM

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Abstract

The invention provides a Chinese medicinal composition. The Chinese medicinal composition fulfills the aim of treating chloasma by removing oxygen radicals. To fulfill the aim, the adopted technical scheme is that: the Chinese medicinal composition is prepared from the following active ingredients in part by weight: 30 to 50 parts of asparagus juice, 20 to 40 parts of bletilla striata, 10 to 30 parts of angelica dahurica, 1 to 3 parts of lithargite, 3 to 7 parts of pearl powder, 1 to 3 parts of bitter apricot seed, and 1 to 3 parts of borneol; and the corresponding preparation method is adopted. The Chinese medicinal composition has the effects of inhibiting tyrosinase activity, reducing generation of melanin, repairing damaged skin fibers, activating histiocytes of skin, delaying skin aging, and treating chloasma.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating chloasma and its preparation method and application. Background technique [0002] Melasma, also known as liver spots and butterfly spots, is a symptom of facial melanosis, which is pigmented spots that occur on the face. Chloasma is mainly caused by endocrine disorders in women, high mental stress, various diseases (liver and kidney insufficiency, gynecological diseases, diabetes), etc., as well as lack of vitamins in the body and external chemical stimulation. [0003] Melasma is a difficult and miscellaneous disease in the world, which seriously plagues hundreds of millions of women. Many women who have experience in freckle removal often spend a lot of money wrongly, and the result becomes more and more serious, so they gradually lose confidence and think that chloasma cannot be cured. [0004] Re...

Claims

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Application Information

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IPC IPC(8): A61K33/24A61P17/00A61K35/56A61K36/898A61K9/06A61K35/618
Inventor 严令耕刘学华赵红影潘苗苗张丽君
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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