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A Xiaoer Xuanfei Zhike Granule Composition and Its Preparation Method and Quality Control Method

A quality control method, the technology of promoting lung and relieving cough, applied in drug combination, measuring device, medical formula, etc., can solve problems such as common side effects, unsatisfactory treatment effect, serious adverse reactions, etc.

Active Publication Date: 2011-12-21
咸阳广泰医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, drug treatment is mainly western medicine treatment and traditional Chinese medicine treatment; western medicine treatment is mainly based on antibiotics, non-steroidal anti-inflammatory drugs, and antihistamines. The side effects of these drugs are more common, and some have serious adverse reactions. Receptivity, very detrimental to children's health
Traditional Chinese medicine is mainly based on Chinese patent medicines in the treatment of colds in children. At present, most of the therapeutic effects on the market are not satisfactory and cannot meet the clinical needs.
[0003] At present, the Chinese patent discloses (the publication number is: CN 1094629A) a prescription and a process of "Xiaoer Yiqi Jiedu Granule and its preparation method". After years of research, the inventor found that the preparation made by the process Existence: unsatisfactory curative effect, low cure rate, easy to relapse; rough process, poor stability, low content of active ingredients, easy to absorb moisture and deteriorate, etc.

Method used

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  • A Xiaoer Xuanfei Zhike Granule Composition and Its Preparation Method and Quality Control Method

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Embodiment 1

[0205] The prescription is:

[0206] Ephedra 105g Bamboo Leaf Fangfeng 210g Southwest Scutellaria baicalensis 210g

[0207] Bellflower 105g Mustard Seed 105g Bitter Almond 105g

[0208] Tinglizi 105g Malan 210g Astragalus 210g

[0209] Yam 105g Hawthorn 210g Licorice 105g

[0210] The preparation method is:

[0211] The above twelve flavors, ephedra are crushed, and 80% ethanol is added for reflux extraction three times, each time for 1.5 hours, the amount of alcohol added is 5, 4, and 3 times respectively, and the ethanol extract is combined, the ethanol is recovered under reduced pressure, and concentrated to a relative density of 1.08 (80-85°C), set aside; the other eleven flavors are crushed, soaked in 90°C water for three times, each time for 1 hour, the amount of water added is 8, 6, and 6 times respectively, combined with warm soaking liquid, filtered, and the filtrate is concentrated to a relatively The density is 1.05 (80-85°C). After cooling to room temperature, ...

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Abstract

The invention relates to a lung-releasing and cough-relieving grain composite for children and a preparation method and a quality control method thereof. The composite is prepared from the following twelve traditional Chinese medicines: Chinese ephedra, Seseli delavayi Franch, Scutellaria amoena, Platycodon grandiflorum, sinapis semina, semen armeniacae amarae, semen lepidii, Indian Kalimeris herb, Astragalus mongholicus, Chinese yam, hawthorn and liquorice. The lung-releasing and cough-relieving grain composite for the children has the effects of releasing lungs, relieving exterior syndromesand clearing heat and eliminating phlegm and is mainly used for treating the external infection cough of the children and cough with excessive phlegm, cough with yellow and thick phlegm as well as choking cough which are caused by phlegm-heat obstructing lung. The lung-releasing and cough-relieving grain composite for the children has an obvious effect in clinical pharmacodynamic study and has high bioavailability and no toxic and side effects.

Description

technical field [0001] The invention relates to a Xiaoer Xuanfeizhike granule composition, a preparation method and a quality control method thereof, and belongs to the technical field of pharmacy. technical background [0002] Infantile cold is a relatively common and frequently-occurring disease in clinical practice. Because children are weak in constitution, they are prone to colds. The main clinical manifestations are fever, cough, and nasal congestion. At present, drug treatment is mainly western medicine treatment and traditional Chinese medicine treatment; western medicine treatment is mainly based on antibiotics, non-steroidal anti-inflammatory drugs, and antihistamines. The side effects of these drugs are common, and some have serious adverse reactions. Receptivity is very detrimental to the health of children. Traditional Chinese medicine is mainly based on Chinese patent medicines in the treatment of infantile colds. Most of the therapeutic effects on the market ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/16G01N30/02G01N30/90A61P11/00
Inventor 王疆宏
Owner 咸阳广泰医药科技有限公司
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