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A traditional Chinese medicine composition for treating post-stroke depression and its preparation method

A technology for post-stroke depression and a composition is applied to a traditional Chinese medicine composition for the treatment of post-stroke depression. The preparation field of the traditional Chinese medicine composition can solve the problems of side effects, slow onset of action, high price, etc., and achieves less toxic and side effects, The effect of reducing depression and strict compatibility

Inactive Publication Date: 2011-11-30
闫咏梅 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The western medicine that is clinically used for the treatment of depression at present mainly divides following several classes: 1. Tricyclic depressants, such as imipramine, amitriptyline etc.; .Monoamine reuptake inhibitors, such as serotonin, norepinephrine reuptake inhibitor maprotiline, selective norepinephrine reuptake inhibitor fluoxetine, paroxetine, etc.; 3. Tetracyclic antidepressants Such as mianserin, triadimefon, etc.; 4. Other types of antidepressants such as phenylpiperazine derivative nefazodone and aminoketone antidepressant bupropion, etc., due to the obvious There are problems such as serious side effects, slow onset, and high price, which limit its application

Method used

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preparation example Construction

[0034] The preparation method of this Chinese medicine composition comprises the following steps:

[0035] Step 1: Weigh the following raw material components by weight percentage: The weight percentage of raw materials for making active ingredients is composed of: Bupleurum bupleurum 14%-20%, Shichangpu 14%-20%, Curcuma 14%-20%, Albizia juniper 14% to 20%, Morinda officinalis 14% to 20%, Polygala 12% to 18%, the total weight percentage of the above components is 100%;

[0036] Step 2: crush the Bupleurum Radix taken in step 1, and set aside;

[0037] Step 3. Add water to decoct the five-flavored traditional Chinese medicines of Shichangpu, turmeric, Albizia juniperus, Morinda officinalis and polygala in step 1. For the first time, add 10 times the total weight of the five-flavored traditional Chinese medicines to decoct for 1-2 hour, filter, and add 8 times the total weight of the five flavors of traditional Chinese medicine for the second time to decoct for 1-2 hours, filte...

Embodiment 1

[0063] Step 1: Weigh the following raw material components by weight percentage: The weight percentage of raw materials for making active ingredients consists of: Bupleurum bupleurum 14%, Shichangpu 19%, Curcuma 20%, Albizia juniper 20%, Morinda officinalis 15%, Polygala 12%;

[0064] Step 2: crush the Bupleurum Radix taken in step 1, and set aside;

[0065] Step 3, adding water and decocting the five-flavored Chinese medicines of Shichangpu, Curcuma turmeric, Albizia Julibrissin, Morinda officinalis and Polygalaceae five-flavored Chinese medicines weighed in step 1, and adding water 10 times the total weight of the five-flavored Chinese medicines for the first time and decocting for 2 hours, Filter, add 8 times the total weight of the five flavors of traditional Chinese medicine for the second time and decoct for 2 hours, filter, combine the two filtrates, concentrate the obtained filtrate into a thick paste with a relative density of 1.30 at a temperature of 50°C, and set as...

Embodiment 2

[0068] Step 1: Weigh the following raw material components by weight percentage: The weight percentage of raw materials for making active ingredients is composed of: Bupleurum 16%, Shichangpu 14%, Curcuma 15%, Albizia Julibrissin 17%, Morinda officinalis 20%, Polygala 18%;

[0069] Step 2: crush the Bupleurum Radix taken in step 1, and set aside;

[0070] Step 3, adding water and decocting the five-flavored Chinese medicines of Shichangpu, Curcuma turmeric, Albizia Julibrissin, Morinda officinalis and Polygalaceae five-flavored Chinese medicines weighed in step 1, adding water of 10 times the total weight of the five-flavored Chinese medicines for the first time and decocting for 1 hour, Filter, add 8 times the total weight of the five traditional Chinese medicines for the second time and decoct for 1 hour, filter, combine the two filtrates, concentrate the obtained filtrate into a thick paste with a relative density of 1.25 at a temperature of 50°C, and set aside ;

[0071]...

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Abstract

The invention discloses a Chinese medicinal composition for treating poststroke depression. The raw materials of the active ingredients of the Chinese medicinal composition comprise the following components in percentage by weight: bupleurum, grassleaf sweelflag rhizome, turmeric root tuber, cortex albiziae, morinda officinalis and thin leaf milkwort root bark. The Chinese medicinal composition is exact in treatment effect and small in toxic and side effect and avoids arousing dependence; and thus, the Chinese medicinal composition can be taken safely and reliably for a long time. The invention also discloses the preparation method of the Chinese medicinal composition comprises the following steps: weighing the components of the raw materials; crushing bupleurum for later use; decocting other five Chinese medicines in water twice, combining filtrate obtained at first time and the filtrate obtained at the second time, concentrating the obtained filtrate into paste, drying the paste at a low temperature, crushing into fine powder, sieving and collecting the undersize powder for later use; and fully mixing the obtained powdered material to obtain the active ingredients of the Chinesemedicinal composition, and preparing required preparations by the conventional preparation method. The steps are simple, the method is easy to implement, and the process is stable.

Description

technical field [0001] The invention belongs to the technical field of Chinese patent medicines, and in particular relates to a traditional Chinese medicine composition for treating post-stroke depression, and also relates to a preparation method of the traditional Chinese medicine composition. Background technique [0002] 1. The hazards of stroke [0003] Stroke is a common and frequently-occurring disease that endangers human life and health. It has the characteristics of high morbidity, high mortality, high disability rate, and high recurrence rate. It ranks the third cause of human death and the first cause of disability. . The "Third National Cause of Death Survey" released by the Ministry of Health of my country in 2008 showed that: cerebrovascular disease is the first cause of death, accounting for 22.45%; 2 million new cases occur each year, 1.5 million people die, 75% become disabled, and relapse within 5 years The rate is 41%; there are 6 million to 7 million pat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/48A61P25/24A61P25/08
Inventor 闫咏梅刘力
Owner 闫咏梅
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