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Collagen-calcium chelate and preparation method thereof

A technology of collagen and calcium chelate, applied in food preparation, food science, application, etc., can solve the problems of low absorption and utilization rate, inability to supplement collagen and calcium together, etc.

Inactive Publication Date: 2011-09-14
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above two types of products all have the defect of low absorption and utilization rate, and there is antagonism between mineral elements, so they cannot fully meet the needs of the body
The third-generation product amino acid chelated calcium has also been developed to a certain extent as an excellent calcium supplement. Although it overcomes the shortcomings of inorganic calcium and organic calcium, it cannot supplement collagen and calcium at the same time.

Method used

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  • Collagen-calcium chelate and preparation method thereof
  • Collagen-calcium chelate and preparation method thereof
  • Collagen-calcium chelate and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Step 1: Weigh 100 mg of animal-derived collagen, dissolve it in 10 mL of double-distilled water, and then add calcium chloride solution with a volume concentration of 10 mg / mL and a volume of 1 mL to the animal-derived collagen solution, and the reaction temperature is 20 ° C. The reaction was carried out for 1.5 hours under stirring conditions, and at the same time, a sodium hydroxide solution with a molar concentration of 0.5 mol / L was added to control the pH value of the reaction solution to 4.0.

[0023] Step 2: After the above reaction is completed, the reaction solution is subjected to vacuum freeze-drying treatment to obtain collagen-calcium chelate.

Embodiment 2

[0025] Step 1: Weigh 100 mg of animal-derived collagen, dissolve it in 10 mL of double-distilled water, and then add calcium chloride solution with a volume concentration of 10 mg / mL and a volume of 1.5 mL to the animal-derived collagen solution, and the reaction temperature is 25 ° C. The reaction was carried out for 2 hours under stirring conditions, and at the same time, a sodium hydroxide solution with a molar concentration of 0.5 mol / L was added to control the pH value of the reaction solution to 4.0.

[0026] Step 2: After the above reaction is completed, the reaction solution is subjected to vacuum freeze-drying treatment to obtain collagen-calcium chelate.

Embodiment 3

[0028] Step 1: Weigh 100 mg of animal-derived collagen, dissolve it in 10 mL of double-distilled water, and then add calcium chloride solution with a volume concentration of 10 mg / mL and a volume of 1.5 mL to the animal-derived collagen solution, and the reaction temperature is 25 ° C. The reaction was carried out for 2.5 hours under stirring conditions, and at the same time, a sodium hydroxide solution with a molar concentration of 0.5 mol / L was added to control the pH value of the reaction solution to 4.0.

[0029] Step 2: After the above reaction is completed, the reaction solution is subjected to vacuum freeze-drying treatment to obtain collagen-calcium chelate.

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Abstract

The invention relates to a collagen-calcium chelate and a preparation method thereof. In traditional calcium preparations, the calcium preparation mainly including inorganic salts and organic salts has low absorption and utilization rates; the amino acid chelated calcium can not supplement collagen and calcium simultaneously; the collagen chelated calcium mainly comprises acid soluble collagen from animal cartilage or skin tissue, and the application of the heterogeneous and xenogenous collagen in human bodies has the risks of high infection rate and high rejection rate. The collagen-calcium chelate provided by the invention is a functional food manufactured by combining calcium elementa with collagen and is prepared from animal-based collagen or humanlike collagen and soluble calcium salts as raw materials through the water system synthesis method. The collagen-calcium chelate has the advantages of good stability and high biological value and can be directly absorbed by the intestinal mucosa to actually realize high absorption, calcium is deposited in the bones under the adhesion of collagen, and the purpose of enhancing the flexibility and the hardness of the bones is finally achieved.

Description

technical field [0001] The invention relates to a collagen-calcium chelate and a preparation method thereof. Background technique [0002] Calcium is one of the most abundant mineral elements in the human body. The total amount in the human body reaches 1300g, which is about 1.5-2.0% of the body weight, of which 99% exists in the bones and teeth. Calcium is fixed in the bone in the form of hydroxyapatite deposition and collagen as the adhesive. If there is no collagen in the bone, it is not called a bone. It is just the accumulation of many hydroxyapatite molecules and particles; if there is not enough collagen in the bone and it is undergoing normal metabolism, it will not be hard and unhealthy. Therefore, to prevent and improve osteoporosis, the most scientific method is to supplement calcium and collagen at the same time. In this way, calcium can be deposited in the bone under the bond of collagen, thereby enhancing the toughness and hardness of the bone. [0003] The ...

Claims

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Application Information

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IPC IPC(8): A23L1/29A23L33/00
Inventor 范代娣马晓轩严建亚张兵
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD
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