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Dynamic PET (polyethylene terephthalate) concentration reconstruction method based on H infinity filtration under constraint of anatomical information

An anatomical information, dynamic technology, applied in image data processing, instrumentation, computing, etc.

Active Publication Date: 2012-08-22
ZHEJIANG UNIV
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Problems solved by technology

[0005] The present invention provides a dynamic PET concentration reconstruction method based on H∞ filtering under the constraints of anatomical information. The dynamic PET reconstruction is guided by the added anatomical information, and the PET image reconstruction model with anatomical information constraints is solved by using the H ∞ filtering algorithm. , which solves the above-mentioned technical difficulties faced by existing reconstruction methods and improves the quality of PET reconstructed images

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  • Dynamic PET (polyethylene terephthalate) concentration reconstruction method based on H infinity filtration under constraint of anatomical information
  • Dynamic PET (polyethylene terephthalate) concentration reconstruction method based on H infinity filtration under constraint of anatomical information
  • Dynamic PET (polyethylene terephthalate) concentration reconstruction method based on H infinity filtration under constraint of anatomical information

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[0044] In order to describe the present invention more specifically, the dynamic PET concentration reconstruction method of the present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0045] Such as figure 1 As shown, a dynamic PET concentration reconstruction method based on H∞ filter under the constraints of anatomical information, including the following steps:

[0046] (1) Obtain anatomical information.

[0047] The anatomical information included in the high-resolution anatomical scan image registered with each frame of dynamic PET image to be estimated is obtained.

[0048] The dynamic PET image refers to starting from the injection of radiopharmaceuticals into the living body, taking the cumulative concentration value of the photon signal emitted in a continuous short time interval as the original projection data of each frame to be estimated, after a series of data correction processing, through eac...

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Abstract

The invention discloses a dynamic PET (polyethylene terephthalate) concentration reconstruction method based on H infinity filtration under constraint of anatomical information, comprising the following steps of: (1) obtaining anatomical information; (2) constructing a PET image reconstruction model with the constraint of anatomical information; and (3) iteratively solving by means of a H infinity filtration algorithm. The dynamic PET concentration reconstruction method based on H infinity filtration under constraint of anatomical information has the advantages that the quality of reconstructed PET image is improved by guiding PET concentration reconstruction while taking the anatomical information as space constraint, the PET image reconstruction model under constraint of anatomical information is solved by means of a H infinity filtration algorithm, the complexity of the system and the uncertainty of the system are adapted preferably, the time relevance of dynamic PET image of each frame is strengthened, the details reconstruction ability of the PET image is improved, the noise of the reconstructed image is improved, the time resolution and space resolution of the reconstructed image can be improved to a certain extent, and the method can be widely applied to the research of pharmacology and neurochemistry and other science field.

Description

technical field [0001] The invention belongs to the technical field of positron emission tomography, and in particular relates to a dynamic PET concentration reconstruction method based on H∞ filtering under the constraint of anatomical information. Background technique [0002] Dynamic positron emission tomography (PET) technology is a living body function display that uses the principle of tracers to collect coincidence counts through continuous scanning in a short time window, and displays biochemical and metabolic information in vivo in real time in the form of anatomical structures. like technology. Because it can provide quantitative parameters describing the process of specific tissue physiological changes, dynamic PET imaging technology is widely used in many scientific fields such as pharmacology and neurochemistry. [0003] The data acquisition time of dynamic PET is short, the coincidence count rate is low, and due to the possible data loss and various noises in ...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T5/10
Inventor 刘华锋张俊超
Owner ZHEJIANG UNIV
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