Sterile ultrasound coupling agent for invasive ultrasound diagnosis and treatment and preparation method thereof

Abstract

The invention relates to a sterile ultrasound gel for invasive ultrasound diagnosis and treatment and a preparation method thereof. The gel comprises the following components in percentage by weight: 0.01 to 0.5 percent of halogenated diphenyl ether or biguanide bactericides, 0.5 to 15 percent of water-soluble chitosan, 0 to 7 percent of dissolving agent, 0.5 to 1.5 percent of water-soluble polymer material, 0.1 to 1 percent of triethanolamine, and the balance of distilled water. The preparation of the sterile ultrasound gel comprises the following steps of: dissolving the halogenated diphenyl ether or the biguanide bactericides into partial distilled water, and standing for 1 to 15 hours; dissolving the water-soluble polymer material into the distilled water to obtain solution, and then dissolving the water-soluble chitosan and the triethanolamine into the distilled water to obtain solution; and adding solution of bactericides into the solution of water-soluble polymer material with stirring, then continuing stirring for 5 to 30 minutes, supplementing the residual distilled water, and then adding the solution of water-soluble chitosan and triethanolamine to obtain the sterile ultrasound gel. The sterile ultrasound gel has the effects of quick broad-spectrum sterilization, stopping bleeding and promoting wound healing, and is more applicable to clinical invasive ultrasound diagnosis and treatment practice.

Description

technical field [0001] The invention relates to a medical ultrasonic coupling agent and a preparation method thereof, in particular to a bactericidal medical ultrasonic coupling agent for invasive medical ultrasonic diagnosis and treatment and a preparation method thereof. Background technique [0002] Medical ultrasonic coupling agent is a sound-transmitting medium widely used in medical ultrasonic diagnosis and treatment at present. Its function is to strengthen the coupling between the ultrasonic probe and human skin, isolate the air between the ultrasonic probe and the skin of the examined part, and make the sound wave conduction unaffected. Attenuated by the influence of air to achieve accurate and clear inspection results. [0003] Since the ultrasonic probe is in contact with the body skin or cavity mucous membrane of the subject, the disinfection treatment of the ultrasonic probe itself becomes very important. However, the existing medical ultrasonic coupling agents...

AI Technical Summary

Problems solved by technology

However, the existing medical ultrasonic coupling agents generally do not have the function of disinfection and sterilization, which leads to the failure of the ultrasonic probe to reach the disinfection level, which violates the national requirements for the use of medical devices in hospitals.

Moreover, in the clinical application of medical ultrasound, there are still the following technical defects: 1. The traditional medical ultrasonic coupling agent only isolates the air and has no sterilization effect; 2. Most disinfectants are corrosive to the ultrasonic probe and cannot be used for disinfection ;3. Because the operating frequency of B-ultrasound is too high, the shorter the disinfection time of the ultrasonic probe, the better, usually about 1 minute

[0004] Although there are a few disinfectant medical ultrasonic coupling agents, their single disinfectant formula is difficult to kill pathogenic microorganisms in about 1 minute

More importantly, due to the limited bactericidal spectrum of a single bactericide component and the fact that the finished product is not thoroughly sterilized, there are still other pathogenic microorganisms in these coupling agents, so they are only suitable for medical ultrasound on intact skin It is not suitable for the examination of mucous membranes or non-intact mucosa, non-intact skin and invasive medical ultrasound practice

Even individual sterile-grade sterile medical ultrasound coupling agents can be used in invasive medical ultrasound practice, but the single bactericide in its formula only has disinfection effect, but has no hemostatic and wound healing effects, and is not completely effective. Facilitating invasive medical ultrasound practice

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