Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine composition for treating iron deficiency anemia and preparation method thereof

A technology for iron deficiency anemia and a composition, which is applied in the field of pharmacy, can solve problems such as malabsorption of iron, and achieve the effects of less dosage, good stability and quick effect.

Active Publication Date: 2011-06-22
SHANDONG WOHUA PHARMACEUTICALS CO LTD
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. Iron malabsorption: iron deficiency anemia due to iron absorption disorder is relatively rare

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition for treating iron deficiency anemia and preparation method thereof
  • Traditional Chinese medicine composition for treating iron deficiency anemia and preparation method thereof
  • Traditional Chinese medicine composition for treating iron deficiency anemia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1. Granules of the present invention

[0042] Prescription: soap alum 4.5g, astragalus 270g, hawthorn 270g, new donkey-hide gelatin 90g, jujube 90g

[0043] Preparation method: Astragalus, hawthorn, and jujube are boiled twice with water for 2 hours each time, the amount of water added is 10 times and 8 times respectively, combined with the decoction, concentrated to a clear paste with a relative density of 1.08 (measured at 80 ° C), added Equal amount (calculated by volume) of 95% ethanol, stand for 48 hours or centrifuge, concentrate the supernatant or centrifuge to a clear paste with a relative density of 1.29-1.31 (measured at 80°C), and filter. Saponin and new donkey-hide gelatin are pulverized, and the fine powder is mixed with the above-mentioned clear paste, powdered sugar, and dextrin to make granules, that is, it is obtained. (1000g granules)

Embodiment 2

[0044] Embodiment 2, the drug effect test of the present invention

[0045] 1 Materials and methods

[0046] 1.1 Sample

[0047] Granules of the present invention: Example 1 of the present invention, the specification is 10g / bag; ferrous sulfate tablets, containing ferrous sulfate content of 0.3g / tablet, are provided by Jinan Yongning Pharmaceutical Co., Ltd., batch number 20051211.

[0048] 1.2 Experimental animals

[0049] 70 female weaned Wistar rats of SPF grade provided by the Laboratory Animal Center of Shandong Medical University were selected, weighing 50-60 g. The breeding environment is a barrier-level animal room, and the license number for the use of experimental animals is SYXK-(Lu) 2006-0025. Low-iron feed was provided by the Chinese Center for Disease Control and Prevention Nutrition and Food Safety.

[0050] 1.3 Dosage selection

[0051] The granules of the present invention are set with low and high dosage groups, which are respectively 0.5 and 1.0 g / kg.B...

Embodiment 3

[0087] Embodiment 3, clinical observation result report is as follows:

[0088] clinical information

[0089] A total of 224 cases of iron deficiency anemia were treated. Among them, there were 32 males and 192 females; the age ranged from 10 months to 79 years, with an average age of 36 years; the time since the onset of symptoms was 1 month to 22 years, and the average disease duration was 5.6 years.

[0090] The 224 cases were divided into three groups for observation: 101 cases in the granule group of the present invention, 93 cases in the Jianpi Shengxue tablet group, and 30 cases in the ferrous sulfate group. A pre-selected observation form was filled out for each case before taking the medicine.

[0091] Treatment and Outcomes

[0092] 1. Treatment

[0093]1. Composition of medicines: Granules of the present invention: (Example 1 of the present invention) provided by Shandong Wohua Pharmaceutical Technology Co., Ltd., and the specification is 10g / bag; etc., produce...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a traditional Chinese medicine composition for treating iron deficiency anemia and a preparation method thereof, belonging to the field of pharmacy. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials of melanterite, radix astragali, haw, new donkey-hide gelatin and Chinese date.

Description

technical field [0001] The invention belongs to the field of pharmacy, and relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating iron deficiency anemia and a preparation method thereof. Background technique [0002] Iron deficiency anemia (iron deficiency anemia, IDA) is a common anemia caused by the lack of iron in the body and affects the synthesis of hemoglobin. Both concentration and serum transferrin saturation were decreased. 典型病例贫血是属于小细胞低色素型。 [0003] 缺铁性贫血是贫血中常见类型,普遍存在于世界各地。 The incidence rate of this anemia is very high in women of childbearing age (especially pregnant women) and infants and young children. The clinical epidemiological survey of high-risk groups in Shanghai area shows that the prevalence rate of iron deficiency anemia in menstrual women, pregnant women and adolescents is 11.39% respectively. \19, 28% and 9.84%, the prevalence of iron deficien...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/734A61P7/06A61K33/26A61K35/36
Inventor 周万辉王冬梅赵磊
Owner SHANDONG WOHUA PHARMACEUTICALS CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com