Method for preparing compound liquoric root tables

A technology of compound licorice tablets and licorice extract powder, applied to medical preparations containing active ingredients, pharmaceutical formulas, plant raw materials, etc., can solve the problems of cumbersome steps, low production capacity, and low efficiency, and achieve simplified process steps and high production efficiency Improve the effect of good efficacy

Active Publication Date: 2012-11-14
INNER MONGOLIA LANTAI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the above-mentioned traditional production process of compound licorice tablets, the three-step process of granulation, drying, and granulation takes a total of 5 hours. The steps are cumbersome, and the production capacity and efficiency are low.

Method used

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  • Method for preparing compound liquoric root tables
  • Method for preparing compound liquoric root tables

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Glycyrrhizae extract powder and sodium benzoate are passed through an 80-mesh sieve, and there is no foreign matter in the appearance after the sieve. 14kg poppy fruit extract powder was mixed with 10kg talcum powder, 20kg licorice extract powder, and 7kg sodium benzoate in a three-dimensional motion mixer with a motor speed of 800 rpm for 10 minutes to obtain mixture A. 51kg of mixture A was mixed with 100kg of licorice extract powder and 10kg of talcum powder in a three-dimensional motion mixer with a motor speed of 800 rpm for 10 minutes to obtain mixture B. 161 kg of mixture B was mixed with 273.75 kg of licorice extract powder and 23.75 kg of talcum powder in a three-dimensional motion mixer with a motor speed of 600 rpm for 40 minutes to obtain mixture C. Dissolve 7kg star anise oil and 7kg camphor in 42.217kg 95% ethanol to make adhesive.

[0017] Put the mixture C in a spray drying granulator, spray the binder into the tank under the pressure of 0.5MPa, set the...

Embodiment 2

[0019] Glycyrrhizae extract powder and sodium benzoate are passed through an 80-mesh sieve, and there is no foreign matter in the appearance after the sieve. 14kg poppy fruit extract powder was mixed with 10kg talcum powder, 20kg licorice extract powder, and 7kg sodium benzoate in a three-dimensional motion mixer with a motor speed of 800 rpm for 10 minutes to obtain mixture A. 51kg of mixture A was mixed with 100kg of licorice extract powder and 10kg of talcum powder in a three-dimensional motion mixer with a motor speed of 800 rpm for 10 minutes to obtain mixture B. 161 kg of mixture B was mixed with 273.75 kg of licorice extract powder and 23.75 kg of talcum powder in a three-dimensional motion mixer with a motor speed of 600 rpm for 40 minutes to obtain mixture C. Dissolve 7kg star anise oil and 7kg camphor in 42.217kg 95% ethanol to make adhesive.

[0020] Put the mixture C in a spray drying granulator, spray the binder into the tank under the pressure of 0.5MPa, set the...

Embodiment 3

[0022] Glycyrrhizae extract powder and sodium benzoate are passed through an 80-mesh sieve, and there is no foreign matter in the appearance after the sieve. 14kg poppy fruit extract powder was mixed with 10kg talcum powder, 20kg licorice extract powder, and 7kg sodium benzoate in a three-dimensional motion mixer with a motor speed of 800 rpm for 10 minutes to obtain mixture A. 51kg of mixture A was mixed with 100kg of licorice extract powder and 10kg of talcum powder in a three-dimensional motion mixer with a motor speed of 800 rpm for 10 minutes to obtain mixture B. 161 kg of mixture B was mixed with 273.75 kg of licorice extract powder and 23.75 kg of talcum powder in a three-dimensional motion mixer with a motor speed of 600 rpm for 40 minutes to obtain mixture C. Dissolve 7kg star anise oil and 7kg camphor in 42.217kg 95% ethanol to make adhesive.

[0023] Put the mixture C in a spray drying granulator, spray the binder into the tank under the pressure of 0.5MPa, set the...

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Abstract

The invention relates to a method for preparing compound liquoric root tables, which comprises the following steps of: sieving liquoric root extract powder and sodium benzoate with a 80-mesh sieve, and detecting whether foreign matters exist in appearance or not after sieving; mixing 14 kilograms of poppy capsule extract powder, 10 kilograms of talcpowder, 20 kilograms of liquoric root extract powder and 7 kilograms of sodium benzoate in a three-dimensional motion mixer of which the rotate speed of a motor is 800 revolutions / minute for 10 minutes to obtain a mixture A; mixing 51 kilograms of mixture A, 100 kilograms of liquoric root extract powder and 10 kilograms of talcpowder in the three-dimensional motion mixer of which the rotate speed of the motor is 800 revolutions / minute for 10 minutes to obtain a mixture B; mixing 161 kilograms of mixture B, 273.75 kilograms of liquoric root extract powder and 23.75 kilograms of talcpowder in the three-dimensional motion mixer of which the rotate speed of the motor is 600 revolutions / minute for 40 minutes to obtain a mixture C; dissolving 7 kilograms of star anise oil and 7 kilograms of camphor in 42.217 kilograms of 95 percent ethanol toprepare a bonding agent; and putting the mixture C in a spray drying pelletizer for 15 to 30 minutes, and spraying the bonding agent into a tank body under the pressure of 0.5 MPa, wherein the air inlet temperature is between 75 and 85 DEG C, and the yield is over 98 percent.

Description

technical field [0001] The invention relates to a new preparation method of compound licorice tablets. Background technique [0002] Compound licorice tablet is a brown or tan tablet made by uniformly mixing licorice extract powder, opium powder (or poppy fruit extract powder), camphor, star anise oil and sodium benzoate. It tastes sweet and has a special smell. It is used for Antitussive and expectorant (see "Chinese Pharmacopoeia" 2005 edition two). [0003] The traditional production process of compound licorice tablets is as follows (take the process of producing 3.5 million finished products as an example): licorice extract powder and sodium benzoate are passed through an 80-mesh sieve, and after sieving, check the appearance for no foreign matter. 14kg poppy fruit extract powder was mixed with 10kg talcum powder, 20kg licorice extract powder, and 7kg sodium benzoate in a three-dimensional motion mixer with a motor speed of 800 rpm for 10 minutes to obtain mixture A. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/66A61K9/20A61P11/10A61P11/14A61K31/125A61K33/12
Inventor 常斌刘芳伟刘文雄梁旭荣
Owner INNER MONGOLIA LANTAI PHARMA
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