Preparation method of solid simulation body for optical breast imaging

Abstract

The invention belongs to the technical field of biomedical engineering and relates to a preparation method of a solid simulation body for optical breast imaging. The preparation method comprises the following steps: dissolving near infrared absorption dye in epoxy resin to prepare absorption mother solution; obtaining the spectral absorption curve of the mother solution, calculating the dosage of the absorption mother solution; calculating the dosage of titanium dioxide required by the simulation body according to the Mie scattering theory; weighting the absorption mother solution, weighting titanium dioxide according to the volume of the required titanium dioxide, mixing titanium dioxide, the absorption mother solution and epoxy resin to fully stir; placing the mixed solution in a vacuum pump, pumping out bubbles; preparing a mould according to the shape and volume of the required simulation body; adding the mixed solution and curing agent in the mould; stirring in a constant speed along one directly to mix evenly; and pumping out bubbles again; and performing low temperature solidification. By adopting the method of the invention, the solid simulation body for optical breast imaging which has stable physical properties and can be stored for long time, can be prepared.

Description

technical field [0001] The invention belongs to the technical field of biomedical engineering, and relates to a method for making an imitation body. Background technique [0002] In the past 30 years, the incidence of breast cancer has been ranked first in the incidence of urban female tumors, and has shown a continuous high growth. Although the treatment technology of breast cancer has been improved, the mortality rate has not decreased significantly. The main reason is that there are more advanced cases and fewer early detection cases. At present, about 1.2 million women in the world suffer from breast cancer every year, and 500,000 women die from breast cancer. Among them, North America and Northern Europe are areas with a high incidence of breast cancer, and its incidence rate is about four times that of Asia, Africa, and Latin America. It has become a heavy burden for European and American countries. However, the mortality rate for breast cancer in the United States h...

AI Technical Summary

Problems solved by technology

The manufacture of breast tissue optical phantoms is still blank in my country, and the liquid phantom production technology based on Intralipid is usually used, which has great limitations in shape control, heterogeneous body embedding and reusability. Although the solid-state phantom independently developed by the research unit can be borrowed, the design methods are different and the production process is confidential, so the imaging target modes available to users are very limited

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