Bezoar antidotal pills (tables and capsules) containing bezoar cultured in vitro and preparation method thereof

A technology for cultivating Niuhuang and Niuhuang Jiedu Pills in vitro, which is applied to medical preparations containing active ingredients, capsule delivery, pill delivery, etc., and can solve the problems of increased toxicity of preparations, etc.

Inactive Publication Date: 2011-06-15
汤明昌 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The original formula contains realgar, which is added into the extract in the form of powder and then granulated and dried. During the manufacturing process of many companies, the drying temperature is mostly 85-105°C, and it takes up to 2 hours to ensure the extract. The drying of the granules meets the moisture requirements of the granules. However, when the extract granules containing realgar and rhubarb powder are baked at 85-105°C for 2 hours, the realgar arsenic in the granules will increase, resulting in an increase in the toxicity of the preparation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Take 5g of in vitro cultured bezoar, 50g of realgar, 200g of gypsum, 200g of rhubarb, 150g of skullcap, 100g of bellflower, 25g of borneol, and 50g of licorice. Crush the realgar into a very fine powder; crush the rhubarb into a fine powder; grind the in vitro cultured bezoar and borneol and sieve through 120 mesh. Mix bellflower, scutellaria baicalensis, gypsum and licorice, add water and decoct twice (the amount of water added each time: 15 times the weight of the medicinal materials), each time for 2 hours, combine the decoctions, filter, and concentrate the filtrate into a thick paste. Add rhubarb and realgar powder to the thick paste to make granules, dry under reduced pressure (drying temperature: 60°C), cool to room temperature, then add in vitro cultured bezoar and borneol powder, mix well, add lubricant, and press into tablets. 1000 tablets (large tablets) or 1500 tablets (small tablets), or coated, ready to serve.

Embodiment 2

[0031] Take 5g of in vitro cultured bezoar, 50g of realgar, 200g of gypsum, 200g of rhubarb, 150g of skullcap, 100g of bellflower, 25g of borneol, and 50g of licorice. Crush the realgar into a very fine powder; crush the rhubarb into a fine powder; grind the in vitro cultured bezoar and borneol and sieve through 120 mesh. Mix bellflower, scutellaria baicalensis, gypsum and licorice, add water and decoct twice (the amount of water added each time: 15 times the weight of the medicinal materials), each time for 2 hours, combine the decoctions, filter, and concentrate the filtrate into a thick paste. Add rhubarb and realgar powder to the thick paste to make granules, dry under reduced pressure (drying temperature: 60°C), cool to room temperature, then add in vitro cultured bezoar and borneol powder, pulverize to make water pan pills (or water honey pan pills) ), polished or coated, that is.

Embodiment 3

[0033]Take 5g of in vitro cultured bezoar, 50g of realgar, 200g of gypsum, 200g of rhubarb, 150g of skullcap, 100g of bellflower, 25g of borneol, and 50g of licorice. Crush the realgar into a very fine powder; crush the rhubarb into a fine powder; grind the in vitro cultured bezoar and borneol and sieve through 120 mesh. Mix bellflower, scutellaria baicalensis, gypsum and licorice, add water and decoct twice (the amount of water added each time: 15 times the weight of the medicinal materials), each time for 2 hours, combine the decoctions, filter, and concentrate the filtrate into a thick paste. Add rhubarb and realgar powder to the thick paste to make granules, dry under reduced pressure (drying temperature: 60°C), cool to room temperature, then add in vitro cultured bezoar and borneol powder, add a small amount of lubricant, and fill capsules into 1000 capsules or 1500 capsules. grain.

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PUM

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Abstract

The invention provides bezoar antidotal pills (tables and capsules) containing bezoar cultured in vitro and a preparation method thereof. Based on weight part, the bezoar antidotal pills (tables and capsules) are prepared from 1 part of bezoar cultured in vitro, 10 parts of realgar, 40 parts of gypsum, 40 parts of rhubarb, 30 parts of baical skullcap root, 20 parts of platycodon root, 5 parts of borneol and 10 parts of liquoric root. Compared with the prior art, the preparation provided by the invention has fewer toxic and side effects and is exact in treatment effectiveness, and the preparation process is more reasonable.

Description

technical field [0001] The invention relates to Niuhuang Jiedu pills (tablets and capsules) containing in vitro cultivated bezoar and a preparation method thereof, belonging to the field of preparation technology of Chinese patent medicines. Background technique [0002] As far as the current medical technology is concerned, there is no very effective and symptomatic drug treatment method for gingival swelling, mouth sores, red eyes and swelling, mainly using antibiotics and other treatment methods, and these methods have obvious defects, and antibiotics are widely abused. , leading to a great increase in the drug resistance of bacteria, and the destruction of the entire immune system of the human body, which can easily lead to the occurrence of complications, and finally infection complications and death. The use of Chinese patent medicines to treat symptoms such as gingival swelling and pain, mouth sores, red eyes, swelling and pain has reliable curative effect and less si...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61K9/20A61K9/48A61P1/02A61P27/02A61P31/00A61K31/045A61K33/06A61K33/36A61K35/413
Inventor 汤明昌
Owner 汤明昌
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