Laser driving needleless injection system

Abstract

The invention relates to a laser driving needleless injection system which adopts laser as driving power, generates high-speed injection flow and realizes needleless injection. The system comprises a laser, an optical fiber and an injector, wherein the laser generates required laser; the beam collimation is adjusted through a beam expander; the laser is focused by a focus lens, and is coupled to the optical fiber; the injector is a piston type injector or a non-piston type injector; the output end of the optical fiber is connected with the kinetic energy chamber part of the injector; liquid is filled in the kinetic energy chamber; and an injection port is arranged at the front end of an administration chamber of the injector. The beam collimation of the laser generated by the laser is adjusted through the beam expander; the laser is focused by the focus lens, is coupled to the optical fiber, and is transmitted to the kinetic energy chamber of the injector to act on the liquid in the chamber; after the liquid absorbs the laser, the liquid is subject to photothermal conversion; and the liquid expands to push the piston so as to act on the administration chamber so that the medicinalliquid is injected to tissues through an injection orifice, or the non-piston injector is utilized to directing act the piston on the medicinal liquid so that the medicament is injected to the administrated position.

Description

technical field [0001] The invention relates to a medical needle-free injection device, in particular to a laser-driven needle-free injection system that uses laser as a driving force to generate high-speed jets and realize needle-free injection. Background technique [0002] For a long time, needle injection has become one of the important ways to prevent and treat diseases. However, there are many adverse reactions of needle injection, such as: acupuncture pain, infection, fat atrophy, fat pad, induration, leakage, needle fainting, broken needle, etc. [0003] In response to the above problems, the development of needle-free injectors began in the 1930s, which used a certain power system to inject drugs at high speed and deliver them to tissues. According to existing reports, the power sources for needle-free injection mainly use spring power, high-pressure gas power, ammunition excitation power, and piezoelectric drive. The development of needle-free injectors has allev...

AI Technical Summary

Problems solved by technology

However, due to the current shortcomings of the needle-free injector, it still cannot better meet the clinical needs.

The main manifestations are: 1. The spring-powered needle-free syringe has poor working stability, which may easily cause differences in dosage

High-pressure gas-powered needle-free injectors produce extremely uncomfortable popping noises, and may cause severe local irritation, with poor safety

The maneuverability of ammunition excitation power is not strong, and it is still in the theoretical stage

Piezoelectric driving power is limited, and it is often used in nano-liter micro-spray therapy, and the amount of jet medicine is small

2. At present, needle-free syringes cannot achieve continuous injection administration, which reduces the efficiency of administration

Needle-free injection requires high-pressure injection to penetrate the skin or tissue, and the injection site is often deep. If it touches the dermis nerves, blood vessels, etc., there may still be pain, bruising and other reactions.

4. With the development of regenerative technology, research on gene and stem cell therapy has become a hotspot, but the current drug delivery method has become one of the bottlenecks restricting its development. If the needle-free injection system can be miniaturized, it can enter the human body through a catheter and exert its high pressure The advantages of spraying, diffusion, efficient absorption, and no needle damage will better promote regenerative treatment

There is currently no needle-free injection method and system using laser actuation

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