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New technology combining reversed micelle and ultrasonic high-efficiency extraction for extracting total saponin of Aralia taibaiensis

A technology of aralia saponin and reverse micelle, which is applied in the field of medicine and can solve problems such as industrial production that has not yet been applied

Inactive Publication Date: 2010-12-15
巫军
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Reverse micellar extraction technology is a new type of bioseparation technology. At present, there are relatively few reports on plant extraction, and it has not been applied to industrial production.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Air-dry 800g of dried Aralia, ultrafinely pulverize it, add water and extract it in an ultrasonic extractor, concentrate the extract to a certain volume, and then use reverse micellar technology combined with ultrasonic extraction technology to extract at 30-35°C Sonicate for 10 minutes, then centrifuge at 4000r / min for 10 minutes, mix the saponin-containing reverse micelle system with buffer solution ME, add 75% ethanol for extraction, recover ethanol and buffer solution from the aqueous solution, and dry to obtain 80.35 g of araloside, with a saponin content of 70.3 %.

Embodiment 2

[0017] Air-dry 800g of dried Aralia, ultrafinely pulverize it, add water and extract it in an ultrasonic extractor, concentrate the extract to a certain volume, and then use reverse micellar technology combined with ultrasonic extraction technology to extract at 30-35°C Sonicate for 20 minutes, then centrifuge at 4000r / min for 10 minutes, mix the saponin-containing reverse micelle system with buffer solution ME, add 75% ethanol for extraction, recover ethanol and buffer solution from the aqueous solution, and dry to obtain 117.7g of araloside with a saponin content of 71.2 %.

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PUM

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Abstract

The invention discloses a process for extracting and purifying saponin of Aralia taibaiensis from dry whole herb of araliaceae aralia plant Aralis taibaiensis. The process comprises the following steps of: air-drying the dry Aralis taibaiensis, micro-pulverizing, adding water, extracting in an ultrasonic extractor, and concentrating the extracting solution into certain volume; extracting by using a reversed micelle technology combined with the ultrasonic extraction technology, centrifuging at high speed, mixing a reversed micelle system containing saponin with a buffer solution ME, adding alcohol to extract, recovering the alcohol and the buffer solution from the water solution, and drying to obtain the saponin of Aralia taibaiensis. Experimental researches on the saponin of Aralia taibaiensis prove that the saponin of Aralia taibaiensis has obvious efficacies of resisting diabetes, promoting the secretion and activity of insulin and the like.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a natural medicinal ingredient extracted and separated from the Chinese herbal medicine Aralia chinensis, which has remarkable anti-diabetic and insulin secretion-promoting effects. Background technique [0002] Aralia is a plant of the genus Aralia in the family Araliaceae. It is a wild vegetable eaten by folks in Heilongjiang, Jilin, Liaoning and other places. According to the "Dictionary of Chinese Medicine", it has the functions of invigorating qi and calming the nerves, strengthening essence and nourishing kidneys, expelling wind and activating blood. Treat neurasthenia, rheumatoid arthritis, diabetes, deficiency of yang, weak qi, and deficiency of kidney yang. [0003] In the early 1950s, saponins were isolated from Aralia japonica. Pharmacological experiments in the Soviet Union, Poland, Japan and my country proved that saponins were the main active ingredien...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/25A61P3/10
Inventor 巫军邹峥嵘丁萍月
Owner 巫军
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