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Bragg curve detector for quick measurement in heavy-ion cancer therapy and using method thereof

A detector and heavy ion technology, applied in the field of heavy ion beam treatment of tumors, can solve the problems of the uniformity of the beam profile of the test results and the influence of the stability of the beam intensity

Active Publication Date: 2010-12-08
INST OF MODERN PHYSICS CHINESE ACADEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The test results of the system are also affected by the uniformity of the beam profile and the stability of the beam intensity

Method used

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  • Bragg curve detector for quick measurement in heavy-ion cancer therapy and using method thereof
  • Bragg curve detector for quick measurement in heavy-ion cancer therapy and using method thereof
  • Bragg curve detector for quick measurement in heavy-ion cancer therapy and using method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1: see figure 1 , figure 2 , a fast-measuring Bragg curve detector for heavy ion cancer treatment, comprising an outer frame 1, several unit ionization chambers 2, and water equivalent bodies 3 of different thicknesses are arranged in front of the unit ionization chambers 2; the described The front and rear ends of the outer frame 1 are respectively provided with an incident window 1-1 and an exit window 1-5; between the entrance window 1-1 and the exit window 1-5, a support plate 1-2 with grooves is provided, Signal lead-out board 1-3, high-voltage input board 1-4; the unit ionization chamber 2 includes a signal pole 2-1 connected to the signal lead-out board 1-3, and a high-voltage pole connected to the high-voltage input board 1-4 2-2; the unit ionization chamber 2 and the water equivalent body 3 in front are placed in the support plate 1-2 with grooves. The distance between the unit ionization chamber 2 and the water equivalent body 3 in front is 5 mm.

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Embodiment 2

[0039] Example 2: see figure 1 , figure 2 , a fast-measuring Bragg curve detector for heavy ion cancer therapy. The distance between the unit ionization chamber 2 and the water equivalent body 3 in front is 3 mm. The two electrodes of the unit ionization chamber 2, the signal pole 2-1 is the anode, the high voltage pole 2-2 is the cathode, the distance between the poles is 15mm, and the effective area of ​​the electrodes is 100×100mm 2 It consists of a conductive film and a frame with conductive electrodes. The conductive film is an aluminized polyimide film with a thickness of 7 μm. The unit ionization chamber works in an atmospheric pressure air. When working, the high voltage pole is connected to 300V negative high voltage, and the signal pole is grounded through a large resistor. In this way, the energy loss signal of incident particles in the unit ionization chamber can be obtained by measuring the voltage at both ends of the resistance, thereby obtaining The irradia...

Embodiment 3

[0045] Embodiment 3: see figure 1 , figure 2 , a fast-measurement Bragg curve detector for heavy ion cancer treatment, the distance between the unit ionization chamber 2 and the water equivalent body 3 in front is 1 mm. Two electrodes of the described unit ionization chamber 2, the signal pole 2-1 is an anode, the high voltage pole 2-2 is a cathode, the distance between the poles is 10mm, and the effective area of ​​the electrodes is 200×200mm 2 It consists of a conductive film and a frame with conductive electrodes. Wherein the conductive film is an aluminized polyimide film with a thickness of 15 μm.

[0046] See image 3 : The front end, middle part and rear end of the detector are divided according to the plateau, peak and post-peak regions of the Bragg curve corresponding to the thickness of several groups of water equivalent bodies 3 . For the present embodiment 3, the fast Bragg curve detector used for heavy particle cancer treatment has 60 groups of water equivale...

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Abstract

The invention relates to the field of technology of heavy-ion beam cancer therapy, in particular to a Bragg curve detector and a using method thereof. A Bragg curve detector for quick measurement in heavy-ion cancer therapy comprises an outer frame (1) and a plurality of unit ionization chambers (2), and is mainly characterized in that: water equivalent bodies (3) with different thicknesses are arranged in front of the unit ionization chambers (2); an incidence window (1-1) and an emergence window (1-5) are arranged at front and rear ends of the outer frame (1); a supporting plate (1-2) with a groove, a signal lead-out plate (1-3) and a high-voltage input plate (1-4) are arranged between the incidence window (1-1) and the emergence window (1-5); each unit ionization chamber (2) comprises a signal pole (2-1) which is connected with the signal lead-out plate (1-3) and a high-voltage plate (2-2) which is connected with the high-voltage input plate (1-4); and the unit ionization chambers (2) and the water equivalent bodies (3) in front are arranged inside the supporting plate (1-2) with the groove. The detector can realize Bragg curve measurement on incident particles in ms-order time.

Description

Technical field: [0001] The invention relates to the field of heavy ion beam treatment of tumor technology, in particular to a Bragg curve detector and its application method. Background technique: [0002] Heavy ion beam therapy for tumors is a new method of cancer treatment. Its use in radiation therapy has both biological advantages and dose distribution advantages Bragg peak (most of the ion energy is deposited at the end of the range), which can achieve high precision (millimeter level), high efficacy and high safety in clinical radiation therapy . In the clinical irradiation process of heavy ion cancer therapy, the tumor is divided into several slices for irradiation, and we change the irradiation depth by changing the energy of the beam to realize the irradiation of each tumor slice. Therefore, to ensure that the beam can reach the tumor accurately and safely, it is necessary to accurately measure the dose depth distribution of irradiated particles before irradiatio...

Claims

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Application Information

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IPC IPC(8): G01T1/02G01T1/185
Inventor 徐瑚珊唐彬胡正国徐治国毛瑞士赵铁成陈金达段利敏孙志宇王建松肖国青郭忠言戎欣娟
Owner INST OF MODERN PHYSICS CHINESE ACADEMY OF SCI
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