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Artificial vertebral lamina

A lamina and artificial technology, applied in the field of artificial lamina and devices for fixing the spine, can solve the problems of poor bone conduction and bone induction, unfavorable new bone formation, etc. Effect

Inactive Publication Date: 2012-09-12
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the technical problems of poor osteoconduction and osteoinductive ability of the artificial lamina in the prior art, which is not conducive to the formation of new bone, and to provide an artificial lamina that is more conducive to the growth of new bone

Method used

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  • Artificial vertebral lamina
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  • Artificial vertebral lamina

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The structural representation of the artificial lamina of this embodiment is shown in figure 2 , as shown in the figure, the artificial lamina is a matrix 1 with a substantially herringbone cross-section and an axial length. The matrix 1 includes three concave curved surfaces 2, 3 and 4, and one of the concave curved surfaces 4 The surface is smooth, and the surface of the concave curved surface 4 is covered with anti-adhesion material, and a plurality of small cylinders 5 are arranged on the surfaces of the other two concave curved surfaces 2 and 3, and the height of the cylinders 5 is 1.8-2mm , preferably 1.83mm, and a cross-sectional radius of 0.05 to 0.1mm, preferably 0.1mm; cylinder 5 is rich in BMP (bone morphogenetic protein, osteoinductive protein) particles, and has an inductive effect on new bone formation; the present embodiment The material of artificial lamina can be polycaprolactone-lactic acid / ethanol copolymer (Chinese patent application 200710300691.7)...

Embodiment 2

[0025] The artificial lamina of this embodiment is a further improvement on the basis of the artificial lamina of Embodiment 1, that is, the top of the cylinder 5 is set as a sphere (see image 3 ), the radius of the sphere is 0.2-0.4 mm, preferably 0.2 mm. Setting the top of the cylinder 5 as a sphere can expand the adhesion and contact area between the artificial lamina and the new bone target cells, which is more conducive to the growth and deposition of new bone, and makes the new bone grow and form quickly.

Embodiment 3

[0027] The artificial lamina of this embodiment is a further improvement on the basis of the artificial lamina of Embodiment 1, and small holes 6 are also arranged between cylinders 5 (such as Figure 4 shown), the radius of the small hole 6 is 0.05-0.08 mm, preferably 0.05 mm, and the small hole 6 is depressed on the concave surface of the base 1 . The setting of the small hole 6 allows new bone cells and other functional cells to deposit here, which facilitates the formation of a relatively dense cell population, facilitates the biological interaction between cells, and promotes the differentiation and growth of new bone cells.

[0028] It has been verified by experiments that the artificial lamina of the present invention is gradually degraded during use, and finally completely degraded and absorbed by the human body when new bone is formed, which has high safety.

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Abstract

The invention relates to an artificial neural plate, belonging to the technical field of medical equipment. The artificial neural plate is a matrix with a approximately lambdoid cross section and with an axial length. The matrix comprises three indent curved surfaces, the surface of one indent curved surface is smooth, and the surfaces of the other two indent curved surfaces are provided with a plurality of small cylinders. The invention has the following beneficial effects that the artificial neural plate has simple structure and convenient use, the matrix provided with small cylinders can provide good support for new bone growth and deposition and is favor of growth and deposition of new bones; and the material of the artificial neural plate is a polymer capable of being degraded and absorbed by human body, has strong capability for inducing target cells to be differentiated into bone cells and is favor of better and faster development of new bones.

Description

technical field [0001] The invention relates to a device for fixing the spine in the technical field of medical devices, in particular to an artificial lamina. Background technique [0002] Laminectomy is a commonly used surgical method in spinal surgery. It usually refers to the removal of part or all of the lamina through the posterior approach to expose the spinal canal and clean up the lesions in the spinal canal. However, after the laminectomy, the structure of the posterior column of the spine was destroyed by surgery. In some patients, scar tissue formed in the laminar defect area, which adhered to the dura mater and nerve roots, involved and compressed the nerves, resulting in recurrence of postoperative symptoms, often resulting in postoperative lumbar spine surgery. Failure Syndrome (FBSS) seriously affects the long-term effect of spinal surgery. How to prevent the occurrence of this complication is an urgent issue in the field of spinal surgery. [0003] Artifici...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/44
Inventor 史建刚李陵江贾连顺袁文刘青孙庆文
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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