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Medicinal composition for improving reproductive capability and preparation method and application thereof

A reproductive ability and composition technology, applied in the field of medicine, can solve problems such as peroxidation

Active Publication Date: 2010-11-10
ZHEJIANG MEDICINE CO LTD XINCHANG PHAMACEUTICAL FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It overcomes the defects such as peroxidation caused by using a certain antioxidant alone

Method used

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  • Medicinal composition for improving reproductive capability and preparation method and application thereof
  • Medicinal composition for improving reproductive capability and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Weigh D-α-tocopherol 150g, coenzyme Q 10 5g was added to 295g corn oil, heated and dissolved in a water bath at 50-60°C, and completely dissolved by visual inspection. Selenomethionine 0.14g (containing 50mg selenium) is dissolved in gelatin, and a certain proportion of colorant and opacifying agent can be added to the gelatin to make colored capsules, which are filled and sealed into soft capsules on a rolling press machine to make 1000 capsules. Then go through the processes of shaping, drying, and pill inspection. Each capsule contains vitamin E150mg, coenzyme Q 10 5mg, selenium 50μg.

Embodiment 2

[0061] Weigh 100 g of D-α-tocopherol acetate (in α-tocopherol equivalent), coenzyme Q 10 Add 10g to 285g corn oil, heat and dissolve in a 50-60°C water bath, and dissolve completely by visual inspection. Selenized carrageenan 0.27g (containing 15mg of selenium) is dissolved in gelatin, and a certain proportion of colorant and opacifier can be added to the gelatin to make colored capsules, which are filled and sealed into soft capsules on a roll-type pressing machine to make 1000 capsules. Then go through the processes of shaping, drying, and pill inspection. Each capsule contains vitamin E100mg, coenzyme Q 10 10mg, selenium 15μg.

Embodiment 3

[0063] Weigh DL-α-tocopherol 100g, coenzyme Q 10 Add 5g and 8g of lecithin into 287g of corn oil, and stir evenly. A certain proportion of colorants and opacifiers can be added to the glue to make colored capsules, which are filled and sealed into soft capsules on a rolling press machine, and then go through processes such as shaping, drying, and pill inspection. Each capsule contains vitamin E100mg, coenzyme Q 10 5mg.

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Abstract

The invention relates to the field of medicaments, and provides a medicinal composition for improving reproductive capability and a preparation method and application thereof. The medicinal composition comprises vitamin E, coenzyme Q10 and / or selenium, and can be used for preparing a medicament and a health product for preventing and treating dysgenesis caused by oxidative stress, endocrine disorder or environmental factor induction when serving as a novel high-efficiency antioxidant. The medicinal composition has the advantages of improving the movement and vitality of sperms, increasing the secretion of sex hormones, protecting the functions of ovaries, improving immunity, improving conception rate, ensuring the nutrition of fetuses, and more effectively treating infertility by combining the conventional medicament vitamin E for treating the infertility and a novel therapeutic medicament coenzyme Q10 and / or selenium and applying different mechanisms for treating the infertility. Compared with any one component in the medicinal composition, the medicinal composition can not only effectively improve curative effect, but also overcome the defects when the components are singly used.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a novel pharmaceutical composition for improving reproductive ability, its preparation method and application. Background technique [0002] Generally, the following five conditions must be met for pregnancy: 1. There are mature eggs; 2. There are enough active and healthy sperm; 3. The viscosity of cervical mucus must be conducive to the penetration of sperm; 4. Each channel ( Including the cervix and fallopian tubes) must be unobstructed; 5. The endometrium and the fertilized egg have synchronous development. As long as any one of the links is impaired, infertility can occur. According to the cause of infertility, it can be divided into relative infertility and absolute infertility: relative infertility means that one of the couple hinders conception or reduces fertility for some reason, resulting in temporary infertility. If this factor is corrected, it is still possible Pregnant. A...

Claims

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Application Information

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IPC IPC(8): A61K33/04A61P15/08A61K31/355A61K31/122A61K31/731A61K31/198A61K36/064
Inventor 林爱弟田治科易德平候国枝王奎缪丹丹
Owner ZHEJIANG MEDICINE CO LTD XINCHANG PHAMACEUTICAL FACTORY
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