Progesterone composite preparation for regulating and controlling estrus of goat

A compound preparation and goat technology, which is applied in the direction of medical preparations containing active ingredients, drug combinations, organic active ingredients, etc., can solve the problem of low libido in treated ewes, and achieve the effect of promoting follicle development and improving activity

Inactive Publication Date: 2010-10-13
玉门中汇农业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The problems with this method are mainly the low conception rate of the ewes in estrus and the low libido of the ewes.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Preparation of spring-winter preparations:

[0049] 1. Drug weighing

[0050] Weigh 30 mg of progesterone and 1.2 mg of estradiol with an analytical balance, and crush them respectively.

[0051] 2. Take 0.38ml of sterilized edible vegetable oil and heat it to 250°C for 20 minutes in a glass dish, then cool it to 50°C, add crushed progesterone and estradiol; stir and dissolve; pour the dissolved medicinal liquid into In another container, continue to heat the undissolved medicinal solution to 80°C and let it stand for 30 minutes; mix the twice dissolved medicinal solutions evenly.

[0052] 3. Seal the mixed medicinal solution into 50ml, 100ml, and 200ml glass bottles respectively, and label them for use.

[0053] The administration procedure of this preparation is as follows:

[0054] (1) Marking of ewes: the method of combining random numbers on the back and registration of ear numbers;

[0055] (2) Intramuscular injection of compound progesterone preparation: 3 ml...

Embodiment 2

[0065] Preparation of summer-autumn formulations:

[0066] 1. Drug weighing

[0067] Weigh 24 mg of progesterone and 1 mg of estradiol with an analytical balance, and crush them respectively.

[0068] 2. Take 0.5ml of sterilized edible vegetable oil and heat it in a glass dish to 250°C for 20 minutes, then cool it to 50°C, add crushed progesterone and estradiol; stir and dissolve; pour the dissolved medicinal liquid into In another container, continue to heat the undissolved medicinal solution to 70°C and let it stand for 30 minutes; mix the twice dissolved medicinal solutions evenly.

[0069] 3. Seal the mixed medicinal solution into 50ml, 100ml, and 200ml glass bottles respectively, and label them for use.

[0070] The treatment method of the preparation is the same as that in Example 1.

Embodiment 3

[0072] For young ewes, the total dose per head is 3.0 ml in spring-winter:

[0073] 1. Drug weighing

[0074] Weigh progesterone 26 mg and estradiol 0.9 mg with an analytical balance, and crush them respectively.

[0075] 2. Take 0.81ml of sterilized edible vegetable oil, heat it in a glass dish to 250°C and keep it for 20min, then cool it to 50°C, add crushed progesterone and estradiol; stir and dissolve; pour the dissolved medicinal liquid into In another container, continue to heat the undissolved medicinal solution to 80°C and let it stand for 30 minutes; mix the twice dissolved medicinal solutions evenly.

[0076] 3. Seal the mixed medicinal solution into 50ml, 100ml, and 200ml glass bottles respectively, and label them for use.

[0077] The treatment method of the preparation is the same as that in Example 1.

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PUM

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Abstract

The invention discloses a progesterone composite preparation for regulating and controlling estrus of a goat. The progesterone composite preparation is characterized by comprising a spring-winter preparation and a summer-autumn preparation, wherein the spring-winter preparation comprises 85.71 to 86.67 percent of progesterone, 3.00 to 3.43 percent of estradiol and 10.33 to 10.86 percent of edible vegetable oil; and the summer-autumn preparation comprises 68.57 to 80.00 percent of progesterone, 1.00 to 3.30 percent of estradiol and 16.70 to 28.57 percent of edible vegetable oil. When used for pre-processing, the progesterone composite preparation can quickly improve the concentration of the progesterone in the blood of the processed goat in a short time to improve the activity of the ovary of the processed female goat and the sensitivity to gonadotropic hormone so as to stimulate estrogen secretion and promote follicular development and can meet the requirement that the female goat needs a small amount of estrogen and a certain amount of progesterone to act on the sexual centre before representing sexual desire and achieving sexual excitation.

Description

technical field [0001] The invention relates to a hormone preparation injected during goat estrus regulation and treatment, which contains estrogen and progesterone, specifically a progesterone compound preparation for goat estrus regulation and control. Background technique [0002] Goat estrus regulation (estrus of control) is a new reproductive control technology developed in modern goat production in recent years. The so-called synchronous estrus (also known as synchronous estrus) refers to artificially controlling and adjusting the estrus cycle of a group of ewes by stimulating the ovaries with the help of exogenous hormones, so that they can change according to the predetermined requirements, so that the ovarian physiological functions of the treated ewes can be completely normal. Be in the same stage, so that they can concentrate on estrus in a unified time, so as to facilitate the organization of mating and reproduction. The mechanism of ewe estrus regulation is des...

Claims

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Application Information

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IPC IPC(8): A61K31/57A61P15/08A61K31/565
Inventor 张居农
Owner 玉门中汇农业发展有限公司
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