Non-operative adhesive agent

Abstract

The invention discloses a non-operative adhesive agent. A blocking material of the adhesive agent adopts a chitosan medical rod-shaped material and a wrapping material of the adhesive agent adopts a chitosan medical film material to wrap an alpha-cyanoacrylate adhesive; the chitosan medical rod-shaped material is a copolymer of the following raw materials in part by weight: 10 to 75 parts of chitosan, 1 to 45 parts of hyaluronic acid, 0 to 45 parts of polylactic acid and 0 to 20 parts of gelatin; and the chitosan medical film material is a copolymer of the following raw materials in part by weight: 10 to 50 parts of chitosan, 1 to 60 parts of hyaluronic acid, 0 to 35 parts of glycerol and 0 to 45 parts of polylactic acid. The invention also discloses a preparation method of the non-operative adhesive agent. The adhesive agent is a purely natural extract, has low cost and rich source and cannot generate any toxic or side effects when in use. The application of the adhesive to implementation of contraception has the advantages of no operation, little pain and small side effect and cannot influence work and life.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular, the invention is a non-surgical plugging agent. Background technique [0002] At present, surgical sterilization is the main method of female sterilization. However, in terms of acceptability, when choosing between non-surgical ligation and surgical ligation, most women are willing to accept non-surgical ligation because it is less painful than surgical sterilization. Short rest time and no surgical operation are required, which means that the risk of infection, trauma and death is less; secondly, the operation process of non-surgical methods is relatively simple, and after training, medical staff at all levels can operate, so there is an urgent need A safe and highly effective non-surgical sterilization product. [0003] As early as the 1970s, my country carried out scientific and technological research on male and female sterilization adhesives. The medical α-cyanoprop...

AI Technical Summary

Problems solved by technology

However, due to the limited technical level at that time, the actual operation was inconvenient, clinically proved that the doctor was too late to operate, the polymer was hard and brittle, the monomer viscosity was small, easy to flow, and no development, etc., and it was not widely used.

[0004] In the mid-to-late 1990s, my country carried out research on adipine sterilization suppositories. Although this suppository is simple to administer, it lacks a standardized method of use. The specific operation is arbitrary, causing a large number of side effects, and serious complications. ectopic pregnancy occurred after the operation, so the application development was stopped because the potential long-term risk of the drug was not effectively evaluated

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