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Chinese medicinal effective-part composition for treating coronary heart diseases

A composition and coronary heart disease technology, applied in the field of medicine, can solve problems such as backward production technology of the Chinese medicine industry, weak international market competitiveness of the Chinese medicine industry, and low modernization level, and achieve remarkable curative effect

Inactive Publication Date: 2010-09-29
HUNAN UNIV OF CHINESE MEDICINE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the low modernization level of the traditional Chinese medicine industry and other reasons, the Chinese medicine industry generally has many problems such as backward production technology, unstable product quality, and low technological content, resulting in weak international market competitiveness of the Chinese medicine industry, and the Chinese medicine industry is facing severe challenges.

Method used

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  • Chinese medicinal effective-part composition for treating coronary heart diseases
  • Chinese medicinal effective-part composition for treating coronary heart diseases
  • Chinese medicinal effective-part composition for treating coronary heart diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Granule, tablet or capsule dosage form of embodiment 1 pharmaceutical composition of the present invention

[0040] Preparation of granules: adopt the conventional preparation process of granules, take 1.5 parts of total salvianolic acid, 1.5 parts of total saponins of Panax notoginseng, 0.02 part of total alkaloids of Piper longum, 0.02 part of total sesquiterpenes of amber, and appropriate amount of auxiliary materials. Mixing, granulating, sieving, and drying to obtain a pharmaceutical composition in the form of granules.

[0041] Preparation of tablets: The prepared granules are further compressed and dried to obtain 1.5 parts of total salvianolic acid, 1.5 parts of total saponins of Panax notoginseng, 0.02 parts of total alkaloids of Piper longum, and 0.02 parts of total sesquiterpenes of succinate pharmaceutical composition in tablet form.

[0042] Preparation of capsules: put the prepared granules into capsule shells to make capsules, and then obtain 1.2 parts o...

Embodiment 2

[0043] The drop pill dosage form of embodiment 2 compositions of the present invention

[0044] Preparation: adopt the conventional technique for preparing drop pills, take 1.25 parts of total salvianolic acid, 1.2 parts of total saponins of Panax notoginseng, 0.10 part of total alkaloids of Piper longum, 0.08 part of total sesquiterpenes of amber, and appropriate amount of excipients to prepare the pharmaceutical composition drop pills.

Embodiment 3

[0045] The soft capsule dosage form of embodiment 3 compositions of the present invention

[0046] Preparation: adopt the conventional process for preparing soft capsules, take 1.25 parts of total phenolic acids of salvia miltiorrhiza, 1 part of total saponins of Panax notoginseng, 0.12 parts of total alkaloids of Piper longum, 0.07 parts of total sesquiterpenes of amber, appropriate amount of auxiliary materials, mix well, and use gelatin as The capsule shell material is compressed into a soft capsule to obtain the soft capsule of the pharmaceutical composition.

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Abstract

The invention discloses a Chinese medicinal composition for preventing or treating coronary heart diseases. The composition can safely and effectively prevent or treat coronary heart diseases. The composition comprises red sage roots extract taking total phenolic acid of red sage roots as effective parts, radix pseudo-ginseng extract taking total saponin of radix pseudo-ginseng as effective parts, long pepper extract taking total alkaloid of long pepper as effective parts, as well as succinum extract taking total diterpene of succinum as effective parts, and utilizes the therapeutical effect of the compatibility of the components on coronary heart diseases to give play to multi-link multi-channel multi-target effect of promoting blood circulation to remove blood stasis, activating collaterals and relieving pain. The composition can be medically acceptable solid oral preparations, such as tablets, capsules (soft capsules or hard capsules), granules and other types of preparations. The composition is used for treating coronary heart diseases, heart failure, arrhythmia and the like, and has the advantages of use safety, effectiveness, stability, controllability and convenience.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a medicine for treating coronary heart disease, in particular to a medicine composition composed of total salvianolic acid, total saponins of notoginseng, total alkaloids of Piper longum and total sesquiterpenes of succinate. Background technique [0002] Coronary heart disease is one of the major diseases that seriously endanger people's health. Because of its high incidence and high mortality, it has become the "first killer of human beings". According to the latest research results on middle-aged people in China, from 1998 to 2008, the incidence of coronary heart disease in Chinese men increased by 26.1% compared with the same period in the past, and that of women increased by 19%. It is the fastest-rising disease among the causes of death among Chinese residents. With the aging of our society and the change of human life style, China will become a country with a large inciden...

Claims

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Application Information

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IPC IPC(8): A61K36/67A61K47/48A61P9/04A61P9/10A61P9/06A61K35/10A61K47/69
Inventor 蔡光先王宇红张水寒杨永华蔡萍
Owner HUNAN UNIV OF CHINESE MEDICINE
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