Spray taking salbutamol and ambroxol as active ingredients
A technology of albuterol and active ingredients, which is applied in the field of sprays and can solve the problems of low bioavailability of oral preparations
Inactive Publication Date: 2010-08-25
北京利乐生制药科技有限公司
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Pharmacokinetic studies have proved that it metabolizes rapidly in the body, excretes quickly, and has low bioavailability of oral preparations
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Abstract
The invention relates to a spray taking salbutamol and ambroxol as active ingredients, which is prepared from salbutamol and ambroxol or salts thereof, or purified hydrates thereof serving as medicinal active ingredients and pharmaceutically acceptable auxiliary materials. The spray is prepared and developed by adding some specific types of auxiliary materials in certain proportions into the salbutamol and ambroxol or the salts thereof, or the purified hydrates thereof serving as raw materials according to the technological measure stated by the invention.
Description
technical field The invention relates to a spray which takes albuterol, ambroxol or salts thereof or purified hydrates thereof as active components. It belongs to the field of medical technology. Background technique Respiratory system disease is a common and frequently-occurring disease that endangers people's health, and its incidence rate accounts for the first among many diseases in any age group. According to data from the Statistical Yearbook of the United States, among all causes of death, the cause of death related to respiratory diseases (excluding tumors) rose from the 10th in 1970 to the 4th in 1991 (chronic obstructive pulmonary disease). and No. 8 (pneumonia, influenza and upper respiratory tract infection). The British Society for Thoracic Surgery pointed out in a recent research report that respiratory diseases have replaced cancer and heart disease as the disease with the highest death rate in the UK. In the UK, respiratory diseases such as pneumonia and l...
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IPC IPC(8): A61K31/137A61K9/12A61P11/00A61P11/06A61P11/08
Inventor 陈瑞晶
Owner 北京利乐生制药科技有限公司
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