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Traditional Chinese medicine preparation with effect of lowering blood sugar, preparation method and application thereof

A traditional Chinese medicine preparation and hypoglycemic technology, which is applied in the directions of medical preparations, pharmaceutical formulations, and drug combinations containing active ingredients, can solve the problems that are not involved or do not involve the pharmacodynamics of Hubei Begonia, and achieve the improvement of dry mouth and throat. , obvious curative effect, good hypoglycemic effect

Active Publication Date: 2010-06-16
LINYI SHANSONG BIOLOGICAL PRODS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent CN101199301 discloses the preparation method of Hubei crabapple brick tea, teabags, concentrated tea tablets and Hubei crabapple pigment, and discloses the application of Hubei crabapple tea in lowering blood sugar and blood fat, but the patent does not involve the extraction of Hubei crabapple And the pharmacodynamic effects of combined medication with oligosaccharides and plant peptides
None of the above four patents involves the effect of the compound recipe composed of Hubei crabapple, soybean oligosaccharides and soybean peptides in the treatment of diabetes

Method used

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  • Traditional Chinese medicine preparation with effect of lowering blood sugar, preparation method and application thereof
  • Traditional Chinese medicine preparation with effect of lowering blood sugar, preparation method and application thereof
  • Traditional Chinese medicine preparation with effect of lowering blood sugar, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 A kind of tablet preparation method with hypoglycemic effect, the steps are as follows:

[0025] (1) Preparation of Hubei Begonia Extract: Take 5kg of Hubei Begonia dried leaves, add 25kg of edible ethanol with a concentration of 30%, and reflux for extraction. The extracts were combined 4 times and ethanol was recovered. The extract was concentrated to 20Bx, the concentrated solution was allowed to stand at 4°C for 24h, centrifuged, and then concentrated to 40Bx for later use.

[0026] (2) Preparation process of preparation: add 20kg of water in the tank, heat to 40°C, add 10kg of soybean peptide powder and 5kg of soybean oligosaccharide with a concentration of 58%, fully stir and mix, then add 2kg of the above-mentioned Hubei Begonia extract, and mix well After that, the temperature was raised to 80° C. for sterilization for 30 minutes, and dried with a belt dryer. After cooling, it is pulverized, and the fine powder is packed in composite plastic bags ...

Embodiment 2

[0031] Embodiment 2 A kind of powder preparation method with hypoglycemic effect, the steps are as follows:

[0032] (1) Preparation of Hubei Begonia Extract: Same as Example 1.

[0033] (2) Extract drying: the above-mentioned preparation liquid is sterilized by flash evaporation unit, and the sterilization temperature is 135 ° C; The powder is packed in a composite plastic bag for use.

[0034] (3) Mixing and milling: weigh 2kg of the above-mentioned fine powder, add 6kg of soybean peptide powder, and 4kg of isomaltooligosaccharide powder, put it into a three-dimensional mixer and mix for 20 minutes, release, measure, and pack in aluminized composite plastic.

[0035] The powder of the invention is obtained through the above steps.

Embodiment 3

[0037] Weigh 2kg of the fine powder obtained in step (2) of Example 2, add 8kg of isomaltooligosaccharide powder, without adding soybean peptide powder, put it into a three-dimensional mixer and mix for 20 minutes, release, measure, and use aluminum-plated composite plastic packaging .

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Abstract

The invention discloses a traditional Chinese medicine preparation with the effect of lowering blood sugar, which comprises the following raw materials in parts by weight: 0.5-60 parts of malus hupehensis extract, 1-95 parts of peptide powder and 2-70 parts of oligosaccharide. The preparation method comprises the following steps: (1) preparing the malus hupehensis extract: taking the dry tree leaves of malus hupehensis, taking ethanol as a solvent, refluxing, extracting, concentrating the extract, standing below 1-4 DEG C, centrifugalizing, removing a precipitate and concentrating supernatant liquid for later use; (2) mixing: adding the peptide powder into water, mixing evenly, regulating the sugar degree, heating, then adding the malus hupehensis extract and the oligosaccharide, mixing evenly, sterilizing and drying to obtain fine powder. The traditional Chinese medicine preparation has burnt odor in smell, is sweet and bitter in taste, has obvious curative effect and good effect of lowering sugar when being used as a medicine for lowering the blood sugar, can obviously improve the clinical symptoms of mouth dryness, throat dryness, polydipsia, frequent micturition with large quantity, myasthenia of limbs, dizziness and the like and has the functions of nourishing yin, tonifying the kidney, supplementing qi, promoting the production of the body fluid and the like.

Description

technical field [0001] The present invention relates to a traditional Chinese medicine preparation with hypoglycemic effect and its preparation method and application. Background technique [0002] Diabetes mellitus, called diabetes mellitus in traditional Chinese medicine, is a series of clinical syndromes caused by absolute or relative lack of insulin in the body. It is a common, frequent and lifelong disease. Its incidence has been increasing year by year, and it has been listed as the third largest disease after cardiovascular disease and tumor in developed countries. At present, diabetes is the most harmful to human health due to a variety of chronic complications based on arteriosclerosis and microvascular disease, such as diabetic heart disease, diabetic gangrene, diabetic cerebrovascular disease, diabetic nephropathy, diabetic retina disease and neuropathy. The number of blind people caused by diabetes is 10 to 25 times more than the average person. At present, dia...

Claims

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Application Information

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IPC IPC(8): A61K38/02A61P3/10A61K31/702A61K36/73
Inventor 周连奎李柱平张立峰
Owner LINYI SHANSONG BIOLOGICAL PRODS
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