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Washing-disinfecting liquid and disinfecting-washing bag thereof for radioactive skin contamination

A technology of radioactive skin and decontamination solution, applied in the direction of skin diseases, organic active ingredients, active ingredients of alkali/alkaline earth metal chlorides, etc., to achieve the effect of small size, less secondary pollution, and high decontamination rate

Inactive Publication Date: 2010-06-16
NAVY MEDICINE RES INST OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no emergency decontamination product for radioactive contamination that does not require water washing and combines the principles of physical adsorption and chemical decontamination.

Method used

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  • Washing-disinfecting liquid and disinfecting-washing bag thereof for radioactive skin contamination
  • Washing-disinfecting liquid and disinfecting-washing bag thereof for radioactive skin contamination
  • Washing-disinfecting liquid and disinfecting-washing bag thereof for radioactive skin contamination

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Embodiment 1, decontamination effect experiment

[0016] 1. Selection and acquisition of radionuclides

[0017] Buy CoCl 2 , by low dose rate fission neutrons ( 252 Cf, absorbed dose rate 0.35mGy / h) irradiated for 2 months to produce activated products 60 Co, 131 I was provided by Huangpu District Central Hospital.

[0018] 2. Establishment of wound and abrasion models

[0019] Small fragrant pigs, 40mg / kg, intraperitoneal injection of pentobarbital sodium, skin preparation, skin well-shaped incision.

[0020] 3. Screening of physical materials

[0021] Select microporous sponges, non-woven fabrics, and medical gauze (materials with high adsorption capacity and gentle contact surface), respectively take materials of the same area and weight, and add physiological saline dropwise until it oozes out to compare water absorption; , skin preparation, cutting 3cm × 3cm, divided into 4 groups (blank group, sponge wiping group, non-woven cloth wiping group, medical gauze...

Embodiment 2

[0049] Embodiment 2, stimulating experiment

[0050] 1. Wound irritation test:

[0051] New Zealand rabbits, 8 rabbits, half male and half male, the hair on both sides of the back was cut short and then depilated. The depilated area was 3cm×3cm each. Group (intact skin group I, damaged skin group II), experimental group (intact skin group III, damaged skin group IV), man-made wounds, take 0.5ml of the decontamination solution of the mixed group (formulation of f) and apply it directly on the wounds , covered and fixed with two layers of gauze (2.5cm×2.5cm) and a layer of cellophane, the skin on the other side was used as a control, and the negative control was smeared and applied for 4 hours. After the test, the residual test sample was removed with warm water. Observe the skin reaction at the site where the test sample was administered 1, 24, 48, and 72 hours after the test sample was removed, and determine the wound irritation intensity. According to the standard score of ...

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Abstract

The invention relates to the technical field of medical instruments, in particular to a washing-disinfecting liquid and a disinfecting-washing bag thereof for skin and wounds with radionuclide contamination. The invention discloses a washing-disinfecting liquid for radioactive skin contamination, which is characterized in that the washing-disinfecting liquid contains 0.5 to 10 percent of EDTA, 0.5 to 10 percent of citric acid, 0.5 to 10 percent of super sodium chloride, and 0.5 to 10 percent of aqueous solution of fatty alcohol sodium sulfate. The invention also discloses a washing-disinfecting bag for radioactive skin contamination, which is characterized in that the washing-disinfecting bag comprises the washing-disinfecting liquid. The washing-disinfecting liquid has the advantages of high decontamination rate and no stimulation to skin or wounds. The washing-disinfecting bag adopting disposable packaging has the characteristics of small volume, convenience for carrying and storage and convenient quick use. When the radionuclide contamination of the skin and the wounds is removed, the washing-disinfecting liquid and the disinfecting-washing bag need no washing, produce little secondary pollution, and ensure good decontamination effects, so the washing-disinfecting liquid and the disinfecting-washing bag can be allocated to personnel engaged in nuclear power, nuclear reactors, radiation devices and other radiation work in the army or local places in order to implement radioactive washing and disinfecting in nuclear accident emergency.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a decontamination solution and a decontamination bag for skin and wounds contaminated with radionuclides. Background technique [0002] At present, there are relatively mature military and commercial technologies for the decontamination of the normal body surface of personnel and large-area decontamination, while the decontamination technology for small sensitive devices and personnel radioactively contaminated wounds is still in the stage of development, exploration and experimentation. For this reason, domestic and international efforts are being made to find effective and applicable technologies and equipment for decontaminating sensitive equipment and personnel wounds. The skin decontaminants commonly used in foreign countries include porous strips, bar soap, anhydrous hand sanitizer, soft brush or LAVA soap. Russia has been equipped with IP P-3 disinfection boxes for...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/14A61P17/16A61K31/255A61K31/198A61K31/194
Inventor 马丽雷呈祥王庆蓉
Owner NAVY MEDICINE RES INST OF PLA
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