Method for preparing total salvianolic acid
A technology of total phenolic acids and lower alcohols of Salvia miltiorrhiza is applied in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., and can solve the problems of poor stability of salvianolic acid, low alcohol precipitation efficiency, total phenolic acid and salvianolic acid. Problems such as low B content
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0060] Danshen decoction pieces 1000 grams, 10000ml60% ethanol reflux extraction three times. The extracts were combined, concentrated to no alcohol, filtered, and the filtrate was passed through a 500 g polyamide column, washed with 10,000 ml of water, eluted with 10,000 ml of 95% ethanol, concentrated eluate, and dried. Obtain 40 grams of extract, the content of salvianolic acid B is 57%, and the total phenolic acid of Salvia miltiorrhiza is 86.6%.
Embodiment 2
[0062] Danshen decoction pieces 1000 grams, 6000m75% methanol extraction three times. The extracts were combined, concentrated to no alcohol, filtered, the filtrate passed through 2000 grams of AB-8 macroporous resin, washed with 15000 ml of water, eluted with 80% ethanol until complete, the eluate was concentrated, and spray-dried. Obtain 45 grams of extract, the content of salvianolic acid B is 64%, and the total phenolic acid of Salvia miltiorrhiza is 93.4%.
Embodiment 3
[0064] Danshen decoction pieces 1000 grams, 15000m75% ethanol countercurrent extraction. The extracts were combined, concentrated to no alcohol, filtered, and the filtrate passed through 2000 grams of D101 macroporous resin resin, rinsed with 15000 ml of 0% ethanol, eluted with 10000 ml of 50% ethanol, concentrated the eluate, and dried in vacuum at 60 degrees. 37 grams of the extract were obtained, the content of salvianolic acid B was 64%, and the total phenolic acids of Salvia miltiorrhiza were 89.5%.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com