Gastrointestinal tract contrast medium

Abstract

The invention discloses a gastrointestinal tract contrast medium and the contrast medium comprises the following components in parts by weight: 1000 parts of purified water, 0.3-20 parts of one or more of pure iodine and iodides in the purified water, and 1-8 parts of edible liquid paraffin, wherein the weight of iodine and iodides is calculated by 100% of pure iodine. The gastrointestinal tract contrast medium has the advantage that the contrast medium is safe and effective and has no toxic and side effects, the contrast medium can be fast filled in the part of body which is needed to imaged, and the contrast medium filled in the intracavity can form imaging oral contrast medium with a certain threshold specific density on the adjacent organ and lesion (nidus). After drunken, the contrast medium of the invention is not easy to absorb and can be discharged fast; the physiochemical performance of the contrast medium is stable, the comparison is obvious, the image is clear, the effective diagnosis rate reaches above 97%, the detecting ability is excellent especially for the observation of midabdomen, lower abdomen and pelvic cavity and the diagnosis of the small lesion (nidus), and the sensitivity and specificity for detecting early tumors and lesions in the gastrointestinal tract can be increased.

Description

Technical field: [0001] The invention relates to a gastrointestinal tract contrast agent, which is used for clinically carrying out CT and MRI abdominal imaging examinations. Scope of application: abdominal and pelvic CT, oral or enema filling preparation before MRI examination, used for CT and MRI gastrointestinal contrast imaging. Background technique: [0002] Early detection and early treatment of tumors is currently a routine clinical method used in various countries, and imaging diagnosis of the gastrointestinal tract using CT and MRI tomographic imaging technologies is a hot spot in international development and research. If CT and MRI gastrointestinal examinations are performed, the contrast medium in the filling cavity must be resolved first. [0003] At present, the clinical gastrointestinal examination is still based on barium meal and gastric and intestinal endoscopy. Compared with CT and MRI, they are unable to observe the lesions outside the cavity, such as th...

AI Technical Summary

Problems solved by technology

Barium swallow or barium enema can only see the outline of the digestive tract, and the barium-filled gastrointestinal radiography often covers tiny lesions. High-density barium agent and low-density air shadow form air barium contrast radiography, and the inspection process is likely to cause positive results

At the same time, barium radiography cannot complete the observation of extracavitary lesions and the identification of overlapping intestinal flexures. Patients generally report that it is difficult to swallow and vomit when barium sulfate is filled.

[0007] 3. Gas contrast agent (air or CO 2 ): It has been used in clinical research in recent years, but it has not been widely used. The reason is that the gas has obvious susceptibility artifacts, and during the scanning process, the patient needs to hold his breath for 2-5 times. Causes image misregistration at the junction of multiple scans

[0011] At present, there is also a prior patent application, which discloses a contrast agent for CT gastrointestinal tract. In this patent application, a cathartic agent is used for the purpose of emptying the contrast agent in the body as soon as possible and shortening the residence time. However, the contrast agent of the gastrointestinal tract The disadvantage is that it is not suitable for patients with mechanical intestinal obstruction, gastrointestinal bleeding and other diseases