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Eriosema chinense isoflavoid extract and extraction method and application thereof

An extraction method and a technology of flavonoids, which are applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc., can solve the problem of unknown active ingredients, inability to clarify the material basis and mechanism of efficacy of traditional Chinese medicine in treating diseases, and restricting applications range and other issues, to achieve the effect of inhibiting ear swelling, good anti-inflammatory effect, and good antibacterial activity

Inactive Publication Date: 2010-03-10
FUJIAN AGRI & FORESTRY UNIV
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  • Abstract
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Problems solved by technology

Although Zhuzai Li has been widely used among the people, there are no relevant literature reports on the active ingredients and biological activities of Zhuzai Li, and the clinical mechanism of Zhuzai Li is not yet clear. The range of clinical application has not been fully and effectively developed and utilized
At the same time, due to the unknown main active ingredients, it is impossible to detect the active ingredients of Zhuzai Li, effectively control the quality of medicinal materials, and conduct authoritative identification of authentic medicinal materials
[0003] Among the many studies of traditional Chinese medicine, there are few studies on active ingredients, pharmacological effects, and the relationship between drug efficacy and ingredients, so it is impossible to clarify the material basis of Chinese medicine efficacy in treating diseases and mechanism of action and other important scientific issues, nor can it provide a lead or structural core for finding new drugs or synthesizing new drugs, and cannot improve the research methods and technical level of new Chinese medicines

Method used

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  • Eriosema chinense isoflavoid extract and extraction method and application thereof
  • Eriosema chinense isoflavoid extract and extraction method and application thereof
  • Eriosema chinense isoflavoid extract and extraction method and application thereof

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Embodiment Construction

[0016] Below in conjunction with embodiment the present invention is described in detail:

[0017] The first part study on the chemical constituents of the petroleum ether extract of piglets

[0018] 1 Experimental instruments and materials

[0019] 1.1 Medicinal materials

[0020] Zhuzai hat was purchased from location: Longyan, Fujian; identification: identification by researcher Wang Zhendeng of Fujian Academy of Traditional Chinese Medicine.

[0021] 1.2 Instruments

[0022] Microanalytical balance (Beijing Sartorius Balance Co., Ltd.); RE-52A rotary evaporator (Shanghai Yarong Biochemical Instrument Factory); constant temperature water bath; partial collector (Shanghai Huxi Analytical Instrument Factory Co., Ltd.); ultrasonic cleaner ( Kunshan Ultrasound Instrument Co., Ltd.); UV-Vis Spectrophotometer (VARIAN, Cary 50); AVATAR360 Infrared Spectrometer (Thermo Nicoler, USA); GS 20 Analytical High Speed ​​Countercurrent Chromatography (Beijing Tianbao Wuhua Biotechnology...

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Abstract

The invention discloses an eriosema chinense isoflavoid extract and an extraction method and applications thereof. The eriosema chinense isoflavoid extract has the structure as the right formula, is prepared by separating and purifying through the combination of HSCCC and traditional thin-layer chromatography preparation by using a traditional solvent backflow extraction method, and is one of thenew compounds which are obtained by separating from the petroleum ether part of eriosema chinense medicinal materials. The eriosema chinense isoflavoid extract of the invention has bacteria-resistant,anti-inflammatory, cough-relieving and sputum-resolving functions.

Description

Technical field: [0001] The invention relates to an extract of flavonoids from piglets and its preparation method and application, and belongs to the field of medicine. Background technique: [0002] The genus Eriosema chinense Vog is a plant of the genus Fabaceae, about 100 species, distributed in tropical and subtropical regions. According to the "Dictionary of Chinese Medicine", the roots of piglets are used as medicine, which has the effects of clearing away heat and detoxification, generating heat and polydipsia, reducing phlegm and moisturizing the lungs, and relieving cough. Rare and valuable Chinese herbal medicine for injuries and other diseases. Zhuzai Li is mainly used to treat cough and asthma. It has remarkable curative effect, is safe and reliable, cheap and convenient. It is a good resource of Chinese herbal medicine and is worthy of development, research and popularization. Although Zhuzai Li has been widely used among the people, there are no relevant lite...

Claims

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Application Information

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IPC IPC(8): C07D311/32A61K31/352A61P31/00A61P29/00A61P11/14A61P11/12A61P11/10A61P31/04
Inventor 李清禄黄美玲李凌峰李宇翔
Owner FUJIAN AGRI & FORESTRY UNIV
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