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Application of Chinese medicinal composition in preparing medicament for treating xerophthalmia

A technology of composition and traditional Chinese medicine, applied in the direction of drug combination, drug delivery, non-living substance medical raw materials, etc., can solve the problems of the application of undisclosed drug compositions, achieve no drug dependence and tolerance, exact curative effect, no The effect of adverse reactions

Active Publication Date: 2012-09-05
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patent does not disclose the application of the pharmaceutical composition in the preparation of drugs for the treatment of dry eye

Method used

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  • Application of Chinese medicinal composition in preparing medicament for treating xerophthalmia
  • Application of Chinese medicinal composition in preparing medicament for treating xerophthalmia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] In order to facilitate the application of the Chinese medicine composition in the treatment of dry eye, the Chinese medicine composition is prepared as a capsule

[0034] prescription:

[0035] Ginseng 89g Ophiopogon japonicus 112g Cornus officinalis 224g Salvia miltiorrhiza 224g

[0036] Fried Suanzaoren 186g, Sangjisheng 186g, Radix Paeoniae Rubra 89g, Ground Beetle 75g

[0037] Gansong 89g Coptidis 45g Southern Schisandra 67g Keel 149g

[0038] Preparation:

[0039] a) In the above prescription, ginseng was extracted three times with 70% ethanol under reflux, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, ethanol was recovered, concentrated, dried, crushed into fine powder, and set aside;

[0040] b) In the above prescription, Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong are extracted three times with 70% ethanol under reflux, and the extracts are combined, fil...

Embodiment 2

[0046] In order to facilitate the application of the Chinese medicine composition in the treatment of dry eye, the Chinese medicine composition is prepared as a tablet

[0047] prescription:

[0048]Ginseng 45g Ophiopogon japonicus 112g Cornus officinalis 224g Salvia miltiorrhiza 225g Fried jujube seed 186g

[0049] Sangjisheng 186g Radix Paeoniae Rubra 89g Gansong 45g Wood Beetle 35g Coptidis 45g

[0050] Southern schisandra 67g, keel 149g.

[0051] Preparation:

[0052] a) In the above prescription, ginseng was extracted three times with 70% ethanol under reflux, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, ethanol was recovered, concentrated, dried, crushed into fine powder, and set aside;

[0053] b) In the above prescription, Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong are extracted three times with 70% ethanol under reflux, and the extracts are combined, filtere...

Embodiment 3

[0059] In order to facilitate the application of the Chinese medicine composition in the treatment of dry eye, the Chinese medicine composition is prepared as granules

[0060] prescription:

[0061] Ginseng 175g Ophiopogon japonicus 192g Cornus officinalis 421g Salvia miltiorrhiza 440g Fried jujube seed 395g

[0062] Sangjisheng 396g Radix Paeoniae Rubra 188g Ground Beetle 98g Gansong 188g Coptidis 85g

[0063] Southern schisandra 147g, keel 278g.

[0064] Preparation:

[0065] a) In the above prescription, ginseng was extracted three times with 70% ethanol under reflux, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, ethanol was recovered, concentrated, dried, crushed into fine powder, and set aside;

[0066] b) In the above prescription, Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong are extracted three times with 70% ethanol under reflux, and the extracts are combined, ...

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Abstract

The invention provides application of a Chinese medicinal composition in preparing a medicament for treating xerophthalmia. The Chinese medicinal composition comprises ginseng, dwarf lilyturf root, dogberry, salvia miltiorrhiza, fried spina date seed, Chinese taxillus twig, red paeony root, ground beeltle, nardostachyos root and rhizome and other Chinese medicaments. The clinical experiments prove that Chinese medicinal composition has obvious clinical curative effect of treating the xerophthalmia.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine composition in the preparation of medicine for treating dry eye syndrome, which belongs to the field of Chinese herbal medicine application. Background technique [0002] Dry eye is one of the most common ophthalmic diseases. It is a series of syndromes caused by the imbalance of tear quality and quantity after the secretion of water quality, mucus and lipid on the surface of the eyeball due to various reasons. factor disease. [0003] Dry eye is caused by abnormalities in tear dynamics and abnormalities in the ocular surface epithelium. Owing to the tight association between the ocular surface epithelium and the tear film, they depend on each other and function as a whole rather than in isolation. Tear fluid dynamics includes four processes: 1. Generation of tear fluid; 2. Distribution of tear fluid; 3. Evaporation of tear fluid; 4. Clearance of tear fluid. An abnormality in...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P27/02A61K35/02A61K35/64
Inventor 李向军安军永王超郑立发
Owner HEBEI YILING MEDICINE INST
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