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Application method of natural plant peony extract

A technology of natural plants and application methods, which is applied in the field of application of natural plant peony extracts, can solve problems such as damage to the gastrointestinal digestive system, can not fundamentally improve allergic constitution, etc., and achieve the effect of small side effects

Inactive Publication Date: 2009-12-30
泊恩诗(上海)化妆品有限公司 +4
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the currently synthesized antihistamines have side effects such as drowsiness, thirst, and damage to the gastrointestinal digestive system in clinical use, and there are certain clinical safety problems in long-term use
[0005] Clinically applied antiallergic preparations are limited to temporary relief, but cannot fundamentally improve allergic constitution

Method used

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  • Application method of natural plant peony extract
  • Application method of natural plant peony extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Get peony 100g, extract A is pure water, configure eluent B: deionized water, C: 70% ethanol aqueous solution (V / V), select non-polar resin: D101, former drug: extract: resin: wash Eluent B: Eluent C=1:10:3:12:12.

[0030] Grind peony and soak in extract A at 30°C for 72 hours, concentrate to a drug solution with a crude drug concentration of about 1 mg / ml, absorb with D101, elute with B, discard the eluent, and collect eluent C for elution part. Concentrate to an extract to obtain the peony extract.

Embodiment 2

[0032] Get peony 100g, extract A is pure water, configure eluent B: deionized water, C: 70% ethanol aqueous solution (V / V), select non-polar resin: D101, former drug: extract: resin: wash Eluent B: Eluent C=1:10:3:12:12.

[0033] Grind peony and extract with extract A at 50°C for 5 hours, concentrate to a drug solution with a crude drug concentration of about 1 mg / ml, absorb with D101, elute with B, discard eluent B, collect eluent C and wash Disjointed. Concentrate to an extract to obtain the peony extract.

Embodiment 3

[0035] Get peony 100g, extract A is pure water, configure eluent B: deionized water, C: 70% methanol aqueous solution (V / V), select non-polar resin: D101, original drug: extract: resin: wash Eluent B: Eluent C=1:8:2:9:12.

[0036] Grind peony and extract three times with extract A at 80°C, 2 hours each time, concentrate to a drug solution with a crude drug concentration of about 1mg / ml, after being adsorbed by D101, elute with B, discard eluent B, collect and wash Deagent C elution section. Concentrate to an extract to obtain the peony extract.

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Abstract

The invention relates to an application method of a natural plant peony extract. In the application method, the natural plant peony extract is applied to medicines, cosmetics and health-care foods for suppressing histamine release. The invention adopts a test model suppressing the histamine release of mass cells and validates the irritability-resisting and itching-relieving effects of the natural plant peony extract.

Description

technical field [0001] The invention relates to an effective active ingredient for skin anti-allergy and antipruritic. The active ingredient is a natural plant peony extract, in particular to an application method of the natural plant peony extract. Background technique [0002] Epidemiological surveys in recent years have shown that allergic diseases have an increasing trend year by year, especially allergic reactions caused by environmental factors and anti-hereditary atopic dermatitis, which have become a social phenomenon that cannot be ignored. The emergence of its problems is not only due to the increase of allergens, air pollution, abuse of food and cosmetic additives, but also due to changes in people's eating habits in recent years. The treatment of allergic diseases is usually based on the elimination of allergens, and then selective drug treatment is carried out according to the degree, cause and pathogenesis of clinical symptoms. Common allergies are generally t...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K8/97A61P37/08A61P17/04A23L1/30
Inventor 李成亮
Owner 泊恩诗(上海)化妆品有限公司
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