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Oxidation-resistant and anti-ageing health care product

A health care product and anti-aging technology, which is applied in the direction of medical preparations containing active ingredients, anti-toxins, food preparation, etc., and can solve the problem that the anti-oxidation effect cannot be maximized.

Inactive Publication Date: 2009-10-21
BEIJING UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, people mainly ingest various antioxidants through natural food, nutritious food or individual drugs, and the antioxidant effect is often not able to maximize the benefits. For example, when selenium (Se) and tocopherol (Ve) are taken together, fertility Phenols can exert the best antioxidant effect

Method used

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  • Oxidation-resistant and anti-ageing health care product
  • Oxidation-resistant and anti-ageing health care product
  • Oxidation-resistant and anti-ageing health care product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] [Example 1] Inhibition test on DNA strand damage induced by peroxynitrite

[0019] Grouping: Group 1 positive control group.

[0020] Group 2 negative control group

[0021] Group 3 rosemary extract 1000mg, echinacea extract 1000mg, ascorbic acid 20mg, tocopherol 20mg, sodium selenite 2mg.

[0022] Group 4 tocopherol 2000mg, sodium selenite 20mg.

[0023] Group 5 ascorbic acid 2000mg, sodium selenite 20mg.

[0024] Group 6 Ascorbic acid 1000mg, tocopherol 1000mg, sodium selenite 20mg.

[0025] Test method: the above groups were dilute to 100mL with deionized water, and diluted 500 times before use.

[0026] figure 1 This is the DNA electrophoresis effect diagram of this formula inhibiting DNA strand breaks. Line1 is the positive control - only DNA; Line2 is the negative control - the mixture of DNA and peroxynitrite; Line3-Line6 are the DNA electrophoresis after adding the formula of group 3-group 6 respectively. from figure 1 It can be seen that the DNA structu...

Embodiment 2

[0032] [Example 2] Anti-DNA strand break experiment with different dosage ratios of the same components

[0033] Grouping: Group 1 positive control

[0034] Group 2 negative control

[0035] Group 3 Echinacea purpurea extract 800mg, rosemary extract 800mg, ascorbic acid 50mg, tocopherol 20mg, sodium selenite 2mg.

[0036] Group 4 Echinacea purpurea extract 1000mg, rosemary extract 1000mg, ascorbic acid 50mg, tocopherol 20mg, sodium selenite 2mg.

[0037] Group 5 Echinacea purpurea extract 1000mg, rosemary extract 1000mg, ascorbic acid 150mg, tocopherol 20mg, sodium selenite 2mg.

[0038] Group 6 Echinacea purpurea extract 1200mg, rosemary extract 1200mg, ascorbic acid 150mg, tocopherol 40mg, sodium selenite 2mg.

[0039] Experimental method is with embodiment 1, and experimental result is as follows:

[0040] Table 2 Anti-DNA strand break results of each group

[0041] group

[0042] The above experiments show that after the component composition is determined, ...

Embodiment 3

[0043] [Example 3] Inhibition test of peroxynitrite-induced LDL oxidation and tyrosine nitration

[0044] Grouping: Group 1 deionized water control group

[0045]Group 2 Echinacea purpurea extract 800mg, midarum extract 800mg, ascorbic acid 50mg, tocopherol 20mg, sodium selenite 2mg.

[0046] Group 3 Echinacea purpurea extract 1000mg, rosemary extract 1000mg, ascorbic acid 50mg, tocopherol 20mg, sodium selenite 2mg.

[0047] Group 4 Echinacea purpurea extract 1000mg, rosemary extract 1000mg, ascorbic acid 150mg, tocopherol 20mg, sodium selenite 2mg.

[0048] Group 5 Echinacea purpurea extract 1200mg, rosemary extract 1200mg, ascorbic acid 150mg, tocopherol 40mg, sodium selenite 2mg.

[0049] The above groups were dilute to 100 mL with deionized water and diluted 500 times before use.

[0050] Experimental methods: 1. Using the production of thiobarbituric acid (TBARS) as an index, the inhibitory effect of this formula on the oxidation of low-density lipoprotein (LDL) induce...

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Abstract

The invention discloses an oxidation-resistant and anti-ageing health care product, which belongs to the technical field of functional health care foods. The health care product comprises a health-care formulation which is prepared by evenly mixing a rosemary extract, an echinacea purpurea extract and an ascorbic acid, tocopherol, and sodium selenite and has no toxic side effects. The formulation has special effects of resisting oxidation, resisting ageing, eliminating free radicals, controlling cardiovascular and cerebrovascular diseases and the like, and provides a new formulation choice for the field of the health care foods.

Description

technical field [0001] The invention belongs to the technical field of functional health food. Background technique [0002] Various free radicals exist in living organisms, such as superoxide anion free radicals (O 2 ·- ), hydroxyl radicals (OH ), nitrogen dioxide (NO 2 ) and nitric oxide (NO ) free radicals, etc. Free radicals are the chief culprit of disease and aging. In organisms, once the ability to remove free radicals in the body weakens, diseases will follow. [0003] Studies have found that the occurrence of some diseases such as cardiovascular and cerebrovascular diseases, central nervous system diseases and cancer is not only caused by the oxidation of free radicals, but the rapid combination of free radicals produces an Oxidizing and cytotoxic substances. Peroxynitrite, the product of the rapid combination of nitric oxide and superoxide anion radicals, can mediate the modification and damage of biological macromolecules (DNA, proteins, and lipids). Someone...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61P39/06A23L1/29A61K31/375A61K31/355A61K33/04A61K31/015A23L33/00
Inventor 罗云敬钟濡刚韩治国潘竟林
Owner BEIJING UNIV OF TECH
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