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Dressing production process

A production process and defoaming technology, which is applied in the field of medical supplies, can solve the problems of no support for the drug film, long baking time, and difficult control, and achieve the effects of easy large-scale production, shortened production time, and improved product quality

Active Publication Date: 2009-08-19
WUHAN HUMANWELL MEDICAL SUPPLIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The solution spinning method has the following disadvantages: high cost, complicated process, and great impact on the environment
The cast coating method has the following disadvantages: 1. The product quality is unstable, which is not conducive to large-scale production; 2. The baking time is long and difficult to control; 3. It is impossible to solve the problem that the film and the mold are too tightly pasted and cannot be torn off. 4. There is no effective support for the drug film, so it is troublesome to use

Method used

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  • Dressing production process

Examples

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Effect test

Embodiment 1

[0026] (1) Get 2Kg of carboxymethyl chitosan, add 60Kg of water to fully mix, then use a shear emulsifier to stir at 20°C for 2 hours to make it evenly mixed, and the pressure is 5 × 10 5 Vacuum filtration under the condition of Pa, the pressure is 7×10 5 Degassing under reduced pressure under the condition of Pa; (2) the solution after degassing is poured into the mould with Teflon anti-sticking coating and coated into film; (3) the mould that is coated is put into vacuum oven at Bake at 60°C for 3 hours, and obtain a carboxymethyl chitosan film after demoulding; (4) use a step-by-step laminating machine to cover one side of the carboxymethyl chitosan film with non-woven fabric or polyurethane film, and the other side Cover with release paper, then cut, pack, and sterilize.

Embodiment 2

[0028] (1) Get 1.5Kg of carboxymethyl chitosan, add 75Kg of water to fully mix, and then use a shearing emulsifier to stir for 1 hour at 30°C to make it evenly mixed. 5 Vacuum filtration under the condition of Pa, the pressure is 9×10 5 Degassing under reduced pressure under the condition of Pa; (2) Pour the solution after degassing into the mold and coat it to form a film; (3) Put the coated mold into a vacuum oven and bake it at 40°C for 5 hours, and demold Finally obtain carboxymethyl chitosan film; (4) use step-by-step laminating machine to cover non-woven fabric or polyurethane film on one side of carboxymethyl chitosan film, and the other side covers release paper, and then it Cut, pack, sterilize.

[0029] In the embodiment of the present invention, carboxymethyl chitosan is used as raw material, and sodium alginate, sodium carboxymethyl cellulose, a mixture of carboxymethyl chitosan and sodium alginate or other drugs capable of promoting wound healing can also be used...

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Abstract

The invention discloses a process for producing dressing. The process comprises the following steps that: (1) an officinal quantity of water-soluble drug and purified water are mixed in the mass ratio of 1:20-50, stirred evenly, filtered and subjected to foam removal; (2) a solution after foam removal is poured into a die, baked at a temperature of between 40 and 60 DEG C and then released from the die so as to form a drug membrane; and (3) one surface of the drug membrane is covered with a non-woven fabric or a polyurethane membrane, and the other surface of the drug membrane is covered with release paper, and then the obtained product is cut, packed and disinfected. The production process provided by the invention has the advantages of wide application range, simple process, convenience for scale production, short production time, low cost and little environmental pollution. In addition, as the process adopts the die with a Teflon anti-sticking coating, the drug membrane is easy to peel away from the die and difficult to damage, and the obtained dressing is stable in quality and easy to control.

Description

technical field [0001] The invention relates to a production process of a dressing, which belongs to the field of medical supplies. Background technique [0002] Ideal dressings are usually required to maintain a moist environment on the wound surface, have a good ability to absorb wound secretions, and have a certain strength and toughness; non-toxic, do not produce harmful reactions or irritations to the human body, and have antibacterial effects; storage stability Well, preferably with a degradable effect, etc. [0003] At present, the dressing raw materials that have been studied more mainly include chitosan or its derivatives, sodium alginate, sodium carboxymethyl cellulose, etc. For example, five new wound dressings made of chitosan have been launched in Japan: Beschitin W, Beschitin F, Chitipack C, Chitipack S and Chitipack P. And domestic also has dozens of medical dressing manufacturers to develop medical dressings containing chitosan, and its production mainly ad...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/44A61F13/02A61L15/26A61L15/40
Inventor 陈思全孙云彭琳
Owner WUHAN HUMANWELL MEDICAL SUPPLIES
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