Method for continuously extracting effective ingredients from Semen cassiae under high pressure

Abstract

The invention discloses a method for continuously extracting active ingredients of cassia seed at high pressure, comprising the following steps: (1) breaking: the cassia seed is broken to particles with 30-80 meshes; (2) soaking: the cassia seed and ethanol are mixed according to the material-to-liquid ratio of 1:10-30 for soaking for 30-60 minutes; (3) high-pressure extraction: material liquid obtained in the step (2) is sent to a high-pressure extractor, the material liquid continuously passes an annular working gap of the high-pressure extractor under the action of 30-90Mpa high pressure, so as to collide on a collision ring in the high-pressure extractor at high speed, break cell walls of the cassia seed and lead the active ingredients to be dispersed in solvent; (4) solid-liquid separation: the material liquid after the high-pressure treatment is taken out, and the solid-liquid separation is carried out for obtaining extract liquid and material residue respectively. The process has simple and safe operation.

Description

technical field [0001] The invention relates to a method for extracting Chinese herbal medicines, in particular to a method for continuously extracting active components of Semen Cassiae under high pressure. Background technique [0002] Cassia is the dry mature seed of Cassia obtusifolia L. or C. tora L. of the leguminous plant. It is a commonly used traditional Chinese medicine in clinical practice. It is listed as the top grade in "Shen Nong's Materia Medica". Modern studies have proved that cassia seed has the activities of lowering blood pressure, lowering blood fat, protecting liver and inhibiting bacteria. At the same time, it can be used as food and a good raw material for health drinks. Therefore, Semen Cassiae has extensive research, utilization and development prospects in terms of medicine and health care. At present, the extraction methods of natural medicines include cooking method, reflux extraction, low temperature impregnation, percolation extraction, super...

AI Technical Summary

Problems solved by technology

At present, the extraction methods of natural medicines include cooking method, reflux extraction, low temperature impregnation, percolation extraction, supercritical CO 2 Extraction, microwave extraction, and ultrasonic extraction, but the technical effects are not satisfactory, such as: the biological activity and pharmacological activity of the cassia seed extract are low; the extraction rate of the active ingredients of the cassia seed is low; the extraction time is long and the energy consumption is high; multiple extractions are required In order to fully extract the active ingredients; multiple extractions are required, and the amount of organic solvent used is large, resulting in energy waste; the amount of organic solvent used is large, and there is a problem of organic solvent residue; the cost of organic solvent recovery is high, which increases the production cost of the product

In addition, ultrasonic extraction and microwave extraction methods are not easy to achieve industrial scale

while supercritical CO 2 It is only suitable for extracting fat-soluble substances, and it needs to be carried out under high pressure conditions. The equipment is complicated, the cost is high, and the production cost is too high, which is not conducive to wide application

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