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Method for preventing adhesion and thrombophlebitis

A thrombophlebitis, anti-adhesion technology, applied in medical science, surgery, etc., can solve the problems of endangering the health of patients, bad, ankylosis, etc.

Inactive Publication Date: 2009-04-01
王民 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Adhesions in the abdominal cavity, thoracic cavity, and joints after surgery often cause symptoms such as intestinal obstruction, pericardial constriction, and joint ankylosis, which seriously endanger the health of patients. In order to solve this problem, many people have worked hard for many years Efforts, among which the physical isolation of glucosamine polymer derivatives is one of the methods. However, due to problems in material selection and evaluation methods, adverse events have occurred

Method used

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Embodiment approach

[0010] The method for tissue lubrication protection, adhesion prevention and thrombophlebitis adverse reaction of glucosamine macromolecular derivatives, the structure of glucosamine macromolecular derivatives selected for the implementation of the present invention should be characterized by low deacetylation degree or no deacetylation Acetyl glucosamine macromolecular material, or the macromolecular substance in the colloid solution does not have the characteristic of positive charge, otherwise, the substance will contact with negatively charged platelets and red blood cells in the blood to activate the external coagulation system through surface contact, resulting in thrombus A series of adverse reaction symptoms such as phlebitis and intracapillary coagulation

[0011] The methods for tissue lubrication protection, adhesion prevention and thrombophlebitis adverse reactions of glucosamine macromolecule derivatives can be evaluated by the following tests to determine safe and...

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PUM

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Abstract

The invention relates to a method for preventing adhesion and avoiding thrombophlebitis, the method is designed aiming at medical materials of polymer medical glucosamine, in particular to chitin; the method provides the structural characteristics of anti-adhesion materials, biological performance requirements on surgical anti-adhesion and an assessment method of a safety test for preventing adverse reactions of the thrombophlebitis for the medical materials, avoids the damages on visual and auditory organs caused by the thrombophlebitis due to the blind use of glucosamine molecules with macromolecules and high degree of deacetylation and even avoids the occurrence of blood clotting in capillary vessels.

Description

1. Technical field: [0001] The invention belongs to the field of medical polymer materials. 2. Technical background: [0002] Chitin-like glucosamine polymer derivatives have good tissue compatibility and metabolization, and have been widely used in medical materials and bioengineering. This is a biological material derived from nature. At present, products with a high degree of deacetylation are used, and the degree of deacetylation is used as an evaluation index to measure whether it has medical value. It is believed that the higher the degree of deacetylation, the better, and the superior performance of the material. It is a wrong choice to choose glucosamine derivatives with a high degree of deacetylation for these products to use in vivo surgery to prevent tissue adhesion by physical isolation. Deacetylation After the base, the amino group has a positive charge. Through surface contact, it is adsorbed on the negatively charged particles of red blood cells and platelets...

Claims

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Application Information

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IPC IPC(8): A61L31/04A61L31/14
Inventor 王民郑青山王学文
Owner 王民
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