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Novel fermentation tank

A fermenter, a new type of technology, applied in the field of enzymology or microbiology devices, can solve the problems of short service life, low mechanical strength, difficult to clean, etc., to reduce material and energy consumption, simplify production process, and improve automation level Effect

Inactive Publication Date: 2011-09-07
姜泓芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The earliest membrane bioreactor was aimed at the application of water treatment, and it is also the most mature membrane bioreactor in application so far, but this type of reactor is not suitable for the so-called biological fermentation, which is different from the purpose of the present invention
Existing membrane bioreactors cannot fully meet the requirements of biological fermentation production and application
Lin Xiao's "Inorganic Membrane Bioreactor" (ZL03221776.5) and Lu Fuping's "Using Inorganic Membrane to Realize Microbial In-Situ Separation and Fermentation Method" (CN1908176A) both place the membrane outside the fermenter, and the membrane and the fermenter It is a membrane circulation fermenter through pipelines connected in series; the disadvantage of this type of membrane bioreactor is that when the cells are in the membrane modules and pipelines, conditions such as dissolved oxygen cannot be controlled, and the pump produces violent agitation for the fluid, which is easy to affect cell growth and Metabolism causes damage and easily destroys the stability of the biochemical reaction system
Some people also put organic hollow fiber membranes in fermentation tanks, but these membranes have low mechanical strength, low flux, small processing capacity, difficult cleaning, poor chemical stability, short service life, and are not suitable for use in large bioreactors. use

Method used

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Embodiment Construction

[0028] The present invention will be further described in detail below in conjunction with the drawings.

[0029] Such as figure 1 As shown, the integrated new fermenter includes a tank body 1, a membrane filter 6, and a pipe 4 connected to the membrane filter. The membrane filter 6 is placed inside the tank body 1, and is connected by one end of the pipe 4. The other end passes through the wall of the tank body 1. The membrane filter 6 can be parallel to the longitudinal axis of the tank 1, and the number can be two symmetrically arranged in the tank. The membrane can be a plate membrane, such as figure 2 As shown, it can also be a tubular membrane, the cross-sectional view is as image 3 Shown. The membrane filter 6 can also be installed on the wall of the tank 1 perpendicular to the longitudinal axis of the fermentation tank, such as Figure 4 As shown, the periphery of the membrane filter 6 is provided with a fixing member 7 for supporting and fixing. The connection between ...

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Abstract

The present invention discloses a novel fermentation tank, which comprises a tank body, a membrane filter and a pipeline; wherein, the membrane filter is arranged inside the tank body; one end of the pipeline is connected with the membrane filter in the tank; the other end of the pipeline leads out of the tank or leads out of the tank through a hollow stirring shaft. The membrane filter can be arranged on the wall of the tank through the pipeline or on the hollow stirring shaft, and the included angle between the membrane filter and the longitudinal axis of the tank is between 0 degree and 90degrees. In the process of bio-fermentation, the fermentation tank can carry out membrane separation, the positive pressure inside the fermentation tank or / and the negative pressure outside the fermentation tank ensure that liquid-phase material can permeate the membrane and pass through the pipeline to reach other devices outside the fermentation tank, and suspended cells and intercepted granules are intercepted in the fermentation tank to keep fermenting. The novel fermentation tank utilizes the characteristic of the combination of the fermentation tank and the membrane separation, to realize the coupling of cell culture and product abstraction. The fermentation tank does not affect the growth and metabolism of cells, the reaction effect is good, the biochemical reaction system is stable, moreover, the cost is low, investment is little, and the fermentation tank is applicable to biological reaction.

Description

Technical field [0001] The invention relates to an enzymology or microbiology device, in particular to a biological fermentation tank adopting membrane separation technology. Background technique [0002] Membrane separation technology has the following advantages: it is carried out at room temperature and the conditions are mild; the material has no phase change; the energy consumption is low; the equipment is simple and the operation and control are convenient. Membrane and membrane technology have been widely used in the fields of chemical industry, medicine, food and beverage, electronics and biochemical industry. Membrane Reactor (MBR), an integrated system formed by the organic combination of membrane and bioreactor, has become a research hotspot in recent years. [0003] A variety of membrane bioreactors have been studied so far. The earliest membrane bioreactor is for water treatment applications, and it is also the most mature membrane bioreactor in application so far, b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M1/12C12M1/02
CPCC12M27/02C12M29/04C12M33/14
Inventor 姜泓芳杜爱民
Owner 姜泓芳
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