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Gynostemma pentaphylla extract and preparation method thereof and use thereof in preparing medicine for preventing and treating fatty liver and sub-health

A technology of Gynostemma pentaphyllum extract and fatty liver, which is applied in the field of medicine, can solve the problems that have not been published, and achieve the effects of improving body resistance, anti-myocardial ischemia, heart function, and reducing TG

Active Publication Date: 2011-11-16
GUANGZHOU BAIYUSN HUTCHISON WHAMPOA CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, although there have been many studies on Gynostemma pentaphyllum in the past 20 years, the research and application of the effective ratio between Gynostemma pentaphyllum saponins and Gynostemma polysaccharides has not been published.

Method used

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  • Gynostemma pentaphylla extract and preparation method thereof and use thereof in preparing medicine for preventing and treating fatty liver and sub-health
  • Gynostemma pentaphylla extract and preparation method thereof and use thereof in preparing medicine for preventing and treating fatty liver and sub-health
  • Gynostemma pentaphylla extract and preparation method thereof and use thereof in preparing medicine for preventing and treating fatty liver and sub-health

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Gynostemma polysaccharide and total saponins of Gynostemma pentaphyllum in embodiment 2-6 adopt following steps to extract:

[0026] (1) Take Gynostemma pentaphyllum and put it into an ultrasonic Chinese medicine extraction tank, add 0.5% calcium carbonate fine powder to adjust pH=8-10, add water to extract twice, filter and then carry out vacuum concentration in a two-effect concentration evaporator, vacuum concentration is effective The temperature is controlled at 80-85°C, the vacuum degree is controlled at -0.06-0.07MPa, concentrated to a relative density of 1.15-1.20 (80°C thermal measurement), and allowed to cool.

[0027] (2) Add 95% (v / v) edible ethanol to the concentrate, stir until the alcohol content reaches 59-61% (v / v), let it stand for 12 hours, and take the supernatant; (v / v) Wash twice with edible ethanol, collect the washing liquid and supernatant and combine them for later use.

[0028] (3) After the supernatant is placed in an alcohol recovery tower ...

Embodiment 2

[0031] Embodiment 2 Gypenosides total saponins sheet

[0032] Prescription: Gypenosides 20g Starch 180

[0033] Take the above-mentioned raw materials in a blender and mix them uniformly by the method of equal increase, and press the whole powder into tablets, each tablet weighs 200 mg, and contains 20 mg of total saponins of Gypenoside.

Embodiment 3

[0034] Embodiment 3. Gynostemma pentaphyllum new component A

[0035] Prescription: Gynostemma saponins 20g, Gynostemma polysaccharide 5g, starch 175g

[0036] Take the above-mentioned raw materials Gynostemma saponins and Gynostemma pentaphyllum polysaccharides and mix them uniformly in a blender using the method of equal increase, and press the whole powder into tablets, each tablet is 200 mg, and each tablet contains 20 mg Gynostemma pentaphyllum saponins and 5 mg Gynostemma polysaccharides.

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Abstract

The invention discloses a Gynostemma pentaphyllum extract containing Gynostemma pentaphyllum polysaccharides and Gynostemma pentaphyllum total saponins at a weight ratio of 1:(1-5). The invention also discloses an application thereof in preparing medicaments for preventing and treating fatty liver and sub-health, and a preparation method thereof. The Gynostemma pentaphyllum extract has good effects of preventing and treating fatty liver and sub-health.

Description

technical field [0001] The invention relates to the extract of Gynostemma pentaphyllum and belongs to the field of medicine. Background technique [0002] The main medicinal ingredient of Gynostemma Gynostemma is total saponins of Gynostemma pentaphyllum, which has similar activity to ginsenosides, is non-toxic, and has stable properties. Gynostemma Gynostemma, as an edible traditional Chinese medicine health product, improves the body's resistance through its lipid-lowering, immune regulation and anti-oxidation effects, and then achieves its anti-fatigue and anti-aging effects. [0003] Gypenosides can improve the body's antioxidant capacity, effectively inhibit the formation of lipid peroxidation products; can improve the blood thick, sticky state of hyperlipidemia rats. It can significantly increase the weight of the immune organs thymus and spleen, improve the immune function of mice and significantly increase the activity of superoxide dismutase, inhibit the production...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/424A61P1/16A61P39/06A61K31/715
Inventor 覃仁安李楚源李淑如黄竹英
Owner GUANGZHOU BAIYUSN HUTCHISON WHAMPOA CHINESE MEDICINE
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