Medicinal composition mainly for curing cardiovascular and cerebrovascular diseases and preparation method thereof

Abstract

The invention discloses a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. Through a stability test, a pharmacodynamic screening and verification test and a toxicological test, the composition is determined to comprise the following components of (by weight parts): salvianolic acid A 1-10 and safflower yellow 1-30, preferably salvianolic acid A 1-5 and safflower yellow 20-30, or salvianolic acid A 6-10 and safflower yellow 1-19. The invention also discloses a detection method and an application of the pharmaceutical composition and the preparations thereof. The pharmacological experiment shows that the pharmaceutical composition has good pharmacological effect.

Description

A pharmaceutical composition mainly used for treating cardiovascular and cerebrovascular diseases and its preparation method technical field The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition mainly used for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. Background technique Salvia miltiorrhiza and safflower are classic Chinese medicinal materials with the function of promoting blood circulation and removing blood stasis. The traditional Chinese medicine preparations based on the combination of salvia miltiorrhiza and safflower have been widely recognized clinically, such as Danhong injection, Danhong infusion, Danhong Traditional Chinese medicine preparations such as Huayu Oral Liquid. However, Danhong preparations use danshensu, tanshinone, salvianolic acid, safflower yellow, etc. as active ingredients, and the research on compatibility is based on the origina...

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Problems solved by technology

Check the literature and patents, there is no report on the compatibility of salvianolic acid A and safflower yellow, but there is a compatibility of salvianolic acid and safflower yellow. Although this drug combination has a certain curative effect, because of the prior art There are certain defects: the obtained salvianolic acid is mainly salvianolic acid B, but the batch-level salvianolic acid A cannot be obtained. Therefore, the batch-level salvianolic acid A Whether it can be combined with safflower yellow requires researchers to go through a lot of scientific research experiments to determine

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